Protocols in Human Molecular Genetics

Detalles Bibliográficos
Autor principal: Mathew, Christopher G. (Autor)
Autor Corporativo: SpringerLink (Online service)
Formato: eBook
Lenguaje:English
Publicado: Totowa, NJ : Humana Press : Imprint: Humana, 1992.
Edición:1st ed. 1992.
Colección:Methods in Molecular Biology, 9
Materias:
Acceso en línea:https://doi.org/10.1385/0896032051
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100 1 |a Mathew, Christopher G.  |e author. 
245 1 0 |a Protocols in Human Molecular Genetics  |c by Christopher G. Mathew. 
250 |a 1st ed. 1992. 
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300 |a 472 p.  |b online resource. 
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490 1 |a Methods in Molecular Biology,  |v 9 
505 0 |a The Polymerase Chain Reaction -- Direct DNA Sequencing of Complementary DNA Amplified by the Polymerase Chain Reaction -- Direct Sequencing of PCR-Amplified DNA -- Rapid DNA Sequence Analysis Using Fluorescent Labels -- Detection of Mutations in DNA and RNA by Chemical Cleavage -- Rapid Methods for Detection of Polymorphic Markers in Genomic DNA -- The Analysis of Point Mutations Using Synthetic Oligonucleotide Probes -- Detection of Mutations by the Amplification Refractory Mutation System (ARMS) -- Automated Gene Detection Using the Oligonucleotide Ligation Assay -- Detection of Point Mutations by Denaturing-Gradient Gel Electrophoresis -- The Detection and Mapping of Point Mutations by RNase A Cleavage -- Discontinuous Polyacrylamide Gel Electrophoresis of DNA Fragments -- Extraction and Enzymatic Amplification of DNA from Paraffin-Embedded Specimens -- The Use of the Polymerase Chain Reaction in the Mapping of Human Genes Using Somatic Cell Hybrids -- The Southern Blot -- The Detection of Specific DNA Sequences by Enhanced Chemiluminescence -- Pulsed-Field Gel Electrophoresis -- Cloning from Gels Following Pulse-Field Gel Electrophoresis -- Yeast Artificial-Chromosome (YAC) Cloning Systems -- Gene Targeting for Somatic Cell Manipulation -- In Situ Hybridization of Chromosomes -- DNA Fingerprinting Analysis -- DNA Fingerprinting and Forensic Medicine -- The Detection of Point Mutations in Hemoglobin Defects Using Allele-Specific Oligonucleotide Probes -- Detection of Gene Deletions Using Multiplex Polymerase Chain Reactions -- Application of Pulsed-Field Gel Electrophoresis to Genetic Diagnosis -- Molecular Diagnostics of Cancer -- The Detection of Latent Virus Infection by Polymerase Chain Reaction -- Mapping Inherited Diseases by Linkage Analysis -- Diagnosis of Genetic Disorders with Linked DNA Markers -- Software for Genetic Linkage Analysis -- Creating Animal Models of Genetic Disease -- Molecular Biology and Medicine. 
650 0 |a Human genetics. 
650 1 4 |a Human Genetics. 
710 2 |a SpringerLink (Online service) 
773 0 |t Springer eBooks 
856 4 0 |u https://doi.org/10.1385/0896032051