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02198nam a22002895i 4500 |
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978-1-59259-574-7 |
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20191027061335.0 |
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cr nn 008mamaa |
| 008 |
100301s1997 xxu| s |||| 0|eng d |
| 020 |
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|a 9781592595747
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| 024 |
7 |
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|a 10.1385/089603447X
|2 doi
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| 040 |
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|a Sistema de Bibliotecas del Tecnológico de Costa Rica
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| 245 |
1 |
0 |
|a Drug'DNA Interaction Protocols
|c edited by Keith R. Fox.
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| 250 |
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|a 1st ed. 1997.
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| 260 |
# |
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|a Totowa, NJ :
|b Humana Press :
|b Imprint: Humana,
|c 1997.
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| 300 |
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|a X, 278 p.
|b online resource.
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| 336 |
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|a text
|b txt
|2 rdacontent
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| 337 |
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|a computer
|b c
|2 rdamedia
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| 338 |
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|a online resource
|b cr
|2 rdacarrier
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| 490 |
1 |
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|a Methods in Molecular Biology,
|v 90
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| 505 |
0 |
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|a DNase I Footprinting -- Quantitative DNA Footprinting -- Uranyl Photoprobing of DNA Structures and Drug–DNA Complexes -- Diethylpyrocarbonate and Osmium Tetroxide as Probes for Drug-Induced Changes in DNA Conformation In Vitro -- Footprinting Studies with Nucleosome-Bound DNA -- A Gel Mobility Shift Assay for Probing the Effect of Drug–DNA Adducts on DNA-Binding Proteins -- An Oligonucleotide Crosslinking Assay for the Analysis of Individual Drug–Binding Sites -- DNA Polymerase Inhibition Assay (PIA) for the Detection of Drug–DNA Interactions -- Transcriptional Footprinting of Drug–DNA Interactions -- Determination of the DNA Sequence Specificity of Alkylation Damage Using Cleavage-Based Assays -- PCR-Based Methods for Detecting DNA Damage and Its Repair at the Subgene and Single Nucleotide Levels in Cells -- Analysis of DNA-Binding Antibodies -- Immunofluorescent Staining of Chromosomes with DNA-Binding Antibodies -- Optical Absorbance and Fluorescence Techniques for Measuring DNA–Drug Interactions -- Evaluation of Drug-Nucleic Acid Interactions by Thermal Melting Curves -- Electric Dichroism -- Calorimetric Techniques for Studying Drug–DNA Interactions -- Methods for the Studies of Drug Dissociation from DNA.
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| 650 |
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0 |
|a Medicinal chemistry.
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| 650 |
1 |
4 |
|a Medicinal Chemistry.
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| 700 |
1 |
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|a Fox, Keith R.
|e editor.
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| 710 |
2 |
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|a SpringerLink (Online service)
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| 773 |
0 |
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|t Springer eBooks
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| 856 |
4 |
0 |
|u https://doi.org/10.1385/089603447X
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