Drug'DNA Interaction Protocols
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| Other Authors: | |
| Format: | eBook |
| Language: | English |
| Published: |
Totowa, NJ :
Humana Press : Imprint: Humana,
1997.
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| Edition: | 1st ed. 1997. |
| Series: | Methods in Molecular Biology,
90 |
| Subjects: | |
| Online Access: | https://doi.org/10.1385/089603447X |
Table of Contents:
- DNase I Footprinting
- Quantitative DNA Footprinting
- Uranyl Photoprobing of DNA Structures and Drug-DNA Complexes
- Diethylpyrocarbonate and Osmium Tetroxide as Probes for Drug-Induced Changes in DNA Conformation In Vitro
- Footprinting Studies with Nucleosome-Bound DNA
- A Gel Mobility Shift Assay for Probing the Effect of Drug-DNA Adducts on DNA-Binding Proteins
- An Oligonucleotide Crosslinking Assay for the Analysis of Individual Drug-Binding Sites
- DNA Polymerase Inhibition Assay (PIA) for the Detection of Drug-DNA Interactions
- Transcriptional Footprinting of Drug-DNA Interactions
- Determination of the DNA Sequence Specificity of Alkylation Damage Using Cleavage-Based Assays
- PCR-Based Methods for Detecting DNA Damage and Its Repair at the Subgene and Single Nucleotide Levels in Cells
- Analysis of DNA-Binding Antibodies
- Immunofluorescent Staining of Chromosomes with DNA-Binding Antibodies
- Optical Absorbance and Fluorescence Techniques for Measuring DNA-Drug Interactions
- Evaluation of Drug-Nucleic Acid Interactions by Thermal Melting Curves
- Electric Dichroism
- Calorimetric Techniques for Studying Drug-DNA Interactions
- Methods for the Studies of Drug Dissociation from DNA.