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02714nam a22002895i 4500 |
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978-1-59259-804-5 |
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20191026222618.0 |
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cr nn 008mamaa |
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100301s2004 xxu| s |||| 0|eng d |
| 020 |
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|a 9781592598045
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| 024 |
7 |
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|a 10.1385/1592598048
|2 doi
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| 040 |
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|a Sistema de Bibliotecas del Tecnológico de Costa Rica
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| 245 |
1 |
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|a Trinucleotide Repeat Protocols
|c edited by Yoshinori Kohwi.
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| 250 |
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|a 1st ed. 2004.
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| 260 |
# |
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|a Totowa, NJ :
|b Humana Press :
|b Imprint: Humana,
|c 2004.
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| 300 |
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|a XII, 342 p.
|b online resource.
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| 336 |
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|a text
|b txt
|2 rdacontent
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| 337 |
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|a computer
|b c
|2 rdamedia
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| 338 |
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|a online resource
|b cr
|2 rdacarrier
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| 490 |
1 |
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|a Methods in Molecular Biology,
|v 277
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| 505 |
0 |
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|a Mouse Models of Triplet Repeat Diseases -- Analysis of Triplet Pepeat DNAs and RNAs -- Analysis of Triplet Repeat Replication by Two-Dimensional Gel Electrophoresis -- Genetic Assays for Triplet Repeat Instability in Yeast -- Detection and Isolation of Trinucleotide Repeat Expansions Using the RED Method -- Analysis of Unstable Triplet Repeats Using Small-Pool Polymerase Chain Reaction -- Real-Time RT-PCR for CTG Repeat-Containing Genes -- Detection and Analysis of Polyglutamine-Containing Proteins and Their Aggregates -- Antibodies Against Huntingtin -- Using Antibodies to Analyze Polyglutamine Stretches -- Solubilization of Aggregates Formed by Expanded Polyglutamine Tract Expression in Cultured Cells -- Establishment of Animal and Cultured Cell Models for Trinucleotide Repeat Diseases -- Caenorhabditis elegans as a Model System for Triplet Repeat Diseases -- Monitoring Aggregate Formation in Organotypic Slice Cultures From Transgenic Mice -- The CGG Repeat and the FMR1 Gene -- Analysis of CTG Repeats Using DM1 Model Mice -- Lentiviral-Mediated Gene Transfer to Model Triplet Repeat Disorders -- Mouse Tissue Culture Models of Unstable Triplet Repeats -- In Vivo Analysis of Trinucleotide Repeat Diseases -- Neurotransmitter Receptor Analysis in Transgenic Mouse Models -- Chromatin Immunoprecipitation Technique for Study of Transcriptional Dysregulation in Intact Mouse Brain -- Techniques for Thick-Section Golgi Impregnation of Formalin-Fixed Brain Tissue -- Assessment of Impaired Proteasomal Function in a Cellular Model of Polyglutamine Diseases -- Assessment of In Vitro and In Vivo Mitochondrial Function in Friedreich’s Ataxia and Huntington’s Disease -- Triplet Repeats and DNA Repair -- Oxidative Damage in Huntington’s Disease.
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| 650 |
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|a Cell biology.
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| 650 |
1 |
4 |
|a Cell Biology.
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| 700 |
1 |
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|a Kohwi, Yoshinori.
|e editor.
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| 710 |
2 |
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|a SpringerLink (Online service)
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| 773 |
0 |
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|t Springer eBooks
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| 856 |
4 |
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|u https://doi.org/10.1385/1592598048
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