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03501nam a22003375i 4500 |
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978-1-59745-541-1 |
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20191026102328.0 |
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cr nn 008mamaa |
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100301s2009 xxu| s |||| 0|eng d |
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|a 9781597455411
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|a 10.1007/978-1-59745-541-1
|2 doi
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|a Sistema de Bibliotecas del Tecnológico de Costa Rica
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| 245 |
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|a Toll-Like Receptors
|b Methods and Protocols /
|c edited by Claire E. McCoy, Luke A.J. O'Neill.
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| 250 |
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|a 1st ed. 2009.
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| 260 |
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|a Totowa, NJ :
|b Humana Press :
|b Imprint: Humana,
|c 2009.
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| 300 |
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|a XXIV, 376 p. 71 illus., 5 illus. in color.
|b online resource.
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| 336 |
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|a text
|b txt
|2 rdacontent
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| 337 |
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|a computer
|b c
|2 rdamedia
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| 338 |
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|a online resource
|b cr
|2 rdacarrier
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| 490 |
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|a Methods in Molecular Biology,
|v 517
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|a Methods to Detect and Analyze Toll-Like Receptors -- Expression Analysis of the Toll-Like Receptors in Human Peripheral Blood Mononuclear Cells -- Ligands, Cell-Based Models, and Readouts Required for Toll-Like Receptor Action -- Toll-Like Receptor Interactions Imaged by FRET Microscopy and GFP Fragment Reconstitution -- Predicting Toll-Like Receptor Structures and Characterizing Ligand Binding -- Bioinformatic Analysis of Toll-Like Receptor Sequences and Structures -- Expression, Purification, and Crystallization of Toll/Interleukin-1 Receptor (TIR) Domains -- Methods to Analyze Signal Transduction Downstream of Toll-Like Receptor Stimulation -- Proteomic Analysis of Protein Complexes in Toll-Like Receptor Biology -- 2D-DIGE: Comparative Proteomics of Cellular Signalling Pathways -- MAPPIT (Mammalian Protein–Protein Interaction Trap) Analysis of Early Steps in Toll-Like Receptor Signalling -- Analysis of the Functional Role of Toll-Like Receptor-4 Tyrosine Phosphorylation -- Analysis of Ubiquitin Degradation and Phosphorylation of Proteins -- The Generation of Highly Purified Primary Human Neutrophils and Assessment of Apoptosis in Response to Toll-Like Receptor Ligands -- Cellular Expression of A20 and ABIN-3 in Response to Toll-Like Receptor-4 Stimulation -- Characterisation of Viral Proteins that Inhibit Toll-Like Receptor Signal Transduction -- Genetic Techniques in Toll-Like Receptor Analysis -- Genetic Dissection of Toll-Like Receptor Signaling Using ENU Mutagenesis -- Microarray Experiments to Uncover Toll-Like Receptor Function -- Uncovering Novel Gene Function in Toll-Like Receptor Signalling Using siRNA -- Genotyping Methods to Analyse Polymorphisms in Toll-Like Receptors and Disease -- Toll-Like Receptors and Disease -- Experimental Models of Acute Infection and Toll-Like Receptor Driven Septic Shock -- Toll-Like Receptors and Rheumatoid Arthritis -- Practical Techniques for Detection of Toll-Like Receptor-4 in the Human Intestine -- Toll-Like Receptor-Dependent Immune Complex Activation of B Cells and Dendritic Cells -- Innate Immunity, Toll-Like Receptors, and Atherosclerosis: Mouse Models and Methods -- Generation of Parasite Antigens for Use in Toll-Like Receptor Research -- Biomarkers Measuring the Activity of Toll-Like Receptor Ligands in Clinical Development Programs.
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| 650 |
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|a Immunology.
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| 650 |
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0 |
|a Cytokines.
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| 650 |
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|a Growth factors.
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| 650 |
1 |
4 |
|a Immunology.
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| 650 |
2 |
4 |
|a Cytokines and Growth Factors.
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| 700 |
1 |
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|a McCoy, Claire E.
|e editor.
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| 700 |
1 |
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|a O'Neill, Luke A.J.
|e editor.
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| 710 |
2 |
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|a SpringerLink (Online service)
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| 773 |
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|t Springer eBooks
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| 856 |
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|u https://doi.org/10.1007/978-1-59745-541-1
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