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03743nam a22003135i 4500 |
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978-1-59745-554-1 |
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20191026111950.0 |
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cr nn 008mamaa |
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110414s2009 xxu| s |||| 0|eng d |
| 020 |
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|a 9781597455541
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| 024 |
7 |
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|a 10.1007/978-1-59745-554-1
|2 doi
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| 040 |
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|a Sistema de Bibliotecas del Tecnológico de Costa Rica
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| 245 |
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|a Therapeutic Antibodies
|b Methods and Protocols /
|c edited by Antony S. Dimitrov.
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| 250 |
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|a 1st ed. 2009.
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| 260 |
# |
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|a Totowa, NJ :
|b Humana Press :
|b Imprint: Humana,
|c 2009.
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| 300 |
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|a XVIII, 585 p.
|b online resource.
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| 336 |
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|a text
|b txt
|2 rdacontent
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| 337 |
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|a computer
|b c
|2 rdamedia
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| 338 |
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|a online resource
|b cr
|2 rdacarrier
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| 490 |
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|a Methods in Molecular Biology,
|v 525
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|a Recombinant Antigens -- Therapeutic Antibodies: Current State and Future Trends – Is a Paradigm Change Coming Soon? -- Preparation of Recombinant Viral Glycoproteins for Novel and Therapeutic Antibody Discovery -- Antibody Libraries -- Design of a Human Synthetic Combinatorial Library of Single-Chain Antibodies -- Construction of a Human Antibody Domain (VH) Library -- Generation and Selection of Rabbit Antibody Libraries by Phage Display -- Construction of a Large Naïve Human Phage-Displayed Fab Library Through One-Step Cloning -- Antibody Discovery -- Identification of Target and Function Specific Antibodies for Effective Drug Delivery -- Screening of Specific Internalization Fab Fragment from Human Naive Phage Library by Combinational Bio-Panning -- Competitive Antigen Panning for Selection of HIV-1 Neutralizing Human Monoclonal Antibodies Specific for gp41 -- Selection of Non-aggregating VH Binders from Synthetic VH Phage-Display Libraries -- Isolation of Full-Length IgG Antibodies from Combinatorial Libraries Expressed in Escherichia coli -- Multiplexed Flow Cytometry: High-Throughput Screening of Single-Chain Antibodies -- Human Antibody Repertoires -- Rapid Screening Platform for Stabilization of scFvs in Escherichia coli -- Antibody Engineering -- In Vitro Antibody Affinity Maturation Targeting Germline Hotspots -- Affinity Maturation by Phage Display -- Production of Chimeric Heavy-Chain Antibodies -- Mammalian Cell Display for Antibody Engineering -- Improving Antibody Binding Affinity and Specificity for Therapeutic Development -- Construction and Production of an IgG-Like Tetravalent Bispecific Antibody for Enhanced Therapeutic Efficacy -- Deimmunization of Monoclonal Antibodies -- Anti-CD22 Onconase: Preparation and Characterization -- Antibody–Cytotoxic Agent Conjugates: Preparation and Characterization -- Antibody Preclinical Development -- High-Level Production of a Humanized ImmunoRNase Fusion Protein from Stably Transfected Myeloma Cells -- Antibody Fragment Expression and Purification -- Scaling-Up and Production of Therapeutic Antibodies for Preclinical Studies -- Antibody Production by the Gram-Positive Bacterium Bacillus megaterium -- Neutralization of HIV by Antibodies -- Dynamics of Antibody Domains Studied by Solution NMR -- In Vivo Method for Establishing Synergy Between Antibodies to Epidermal Growth Factor Receptor and Vascular Endothelial Growth Factor Receptor-2 -- Passive Immunization with Human Neutralizing Monoclonal Antibodies Against HIV-1 in Macaque Models: Experimental Approaches -- Antibody Sequence Analysis -- Organizing, Exploring, and Analyzing Antibody Sequence Data: The Case for Relational-Database Managers.
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| 650 |
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|a Immunology.
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| 650 |
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0 |
|a Antibodies.
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| 650 |
1 |
4 |
|a Immunology.
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| 650 |
2 |
4 |
|a Antibodies.
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| 700 |
1 |
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|a Dimitrov, Antony S.
|e editor.
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| 710 |
2 |
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|a SpringerLink (Online service)
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| 773 |
0 |
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|t Springer eBooks
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| 856 |
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|u https://doi.org/10.1007/978-1-59745-554-1
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