Therapeutic Antibodies Methods and Protocols /

Detalles Bibliográficos
Autor Corporativo: SpringerLink (Online service)
Otros Autores: Dimitrov, Antony S. (Editor )
Formato: eBook
Lenguaje:English
Publicado: Totowa, NJ : Humana Press : Imprint: Humana, 2009.
Edición:1st ed. 2009.
Colección:Methods in Molecular Biology, 525
Materias:
Acceso en línea:https://doi.org/10.1007/978-1-59745-554-1
Tabla de Contenidos:
  • Recombinant Antigens
  • Therapeutic Antibodies: Current State and Future Trends – Is a Paradigm Change Coming Soon?
  • Preparation of Recombinant Viral Glycoproteins for Novel and Therapeutic Antibody Discovery
  • Antibody Libraries
  • Design of a Human Synthetic Combinatorial Library of Single-Chain Antibodies
  • Construction of a Human Antibody Domain (VH) Library
  • Generation and Selection of Rabbit Antibody Libraries by Phage Display
  • Construction of a Large Naïve Human Phage-Displayed Fab Library Through One-Step Cloning
  • Antibody Discovery
  • Identification of Target and Function Specific Antibodies for Effective Drug Delivery
  • Screening of Specific Internalization Fab Fragment from Human Naive Phage Library by Combinational Bio-Panning
  • Competitive Antigen Panning for Selection of HIV-1 Neutralizing Human Monoclonal Antibodies Specific for gp41
  • Selection of Non-aggregating VH Binders from Synthetic VH Phage-Display Libraries
  • Isolation of Full-Length IgG Antibodies from Combinatorial Libraries Expressed in Escherichia coli
  • Multiplexed Flow Cytometry: High-Throughput Screening of Single-Chain Antibodies
  • Human Antibody Repertoires
  • Rapid Screening Platform for Stabilization of scFvs in Escherichia coli
  • Antibody Engineering
  • In Vitro Antibody Affinity Maturation Targeting Germline Hotspots
  • Affinity Maturation by Phage Display
  • Production of Chimeric Heavy-Chain Antibodies
  • Mammalian Cell Display for Antibody Engineering
  • Improving Antibody Binding Affinity and Specificity for Therapeutic Development
  • Construction and Production of an IgG-Like Tetravalent Bispecific Antibody for Enhanced Therapeutic Efficacy
  • Deimmunization of Monoclonal Antibodies
  • Anti-CD22 Onconase: Preparation and Characterization
  • Antibody–Cytotoxic Agent Conjugates: Preparation and Characterization
  • Antibody Preclinical Development
  • High-Level Production of a Humanized ImmunoRNase Fusion Protein from Stably Transfected Myeloma Cells
  • Antibody Fragment Expression and Purification
  • Scaling-Up and Production of Therapeutic Antibodies for Preclinical Studies
  • Antibody Production by the Gram-Positive Bacterium Bacillus megaterium
  • Neutralization of HIV by Antibodies
  • Dynamics of Antibody Domains Studied by Solution NMR
  • In Vivo Method for Establishing Synergy Between Antibodies to Epidermal Growth Factor Receptor and Vascular Endothelial Growth Factor Receptor-2
  • Passive Immunization with Human Neutralizing Monoclonal Antibodies Against HIV-1 in Macaque Models: Experimental Approaches
  • Antibody Sequence Analysis
  • Organizing, Exploring, and Analyzing Antibody Sequence Data: The Case for Relational-Database Managers.