Protein-Protein Interactions as New Drug Targets
| Corporate Author: | |
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| Other Authors: | , |
| Format: | eBook |
| Language: | English |
| Published: |
Berlin, Heidelberg :
Springer Berlin Heidelberg : Imprint: Springer,
2008.
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| Edition: | 1st ed. 2008. |
| Series: | Handbook of Experimental Pharmacology,
186 |
| Subjects: | |
| Online Access: | https://doi.org/10.1007/978-3-540-72843-6 |
Table of Contents:
- Organization of Scaffolds
- A-Kinase Anchoring Proteins as the Basis for cAMP Signaling
- Arrestins as Multi-Functional Signaling Adaptors
- Role of Ena/VASP Proteins in Homeostasis and Disease
- Scaffold/Matrix Attachment Regions (S/MARs): Relevance for Disease and Therapy
- Clathrin/AP-2-Dependent Endocytosis: A Novel Playground for the Pharmacological Toolbox?
- Scaffolding Proteins and Cellular Signalling
- PDE4 Associates with Different Scaffolding Proteins: Modulating Interactions as Treatment for Certain Diseases
- G-Protein-Coupled Receptor-Signaling Components in Membrane Raft and Caveolae Microdomains
- Protein Scaffolds, Lipid Domains and Substrate Recognition in Protein Kinase C Function: Implications for Rational Drug Design
- Compartmentalised MAPK Pathways
- Dynamic Protein Complexes Regulate NF-?B Signaling
- An Oncogenic Hub: ?-Catenin as a Molecular Target for Cancer Therapeutics
- A Toolkit for Real-Time Detection of cAMP: Insights into Compartmentalized Signaling
- Cell Type-Specific Anchoring
- Scaffolding Proteins in Cardiac Myocytes
- Molecular Architecture of Signal Complexes Regulating Immune Cell Function
- Scaffolding Proteins at the Postsynaptic Density: Shank as the Architectural Framework
- Interference with Protein-Protein Interaction Sites as a New Pharmacological Concept
- Domains Mediate Protein-Protein Interactions and Nucleate Protein Assemblies
- Proline-Rich Sequence Recognition Domains (PRD): Ligands, Function and Inhibition
- Chemical Inhibition Through Conformational Stabilization of Rho GTPase Effectors
- Pharmacological Interference with Protein-Protein Interactions Mediated by Coiled-Coil Motifs
- Direct AKAP-Mediated Protein-Protein Interactions as Potential Drug Targets.