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02536nam a22003135i 4500 |
| 001 |
978-3-642-67188-3 |
| 005 |
20191025121157.0 |
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cr nn 008mamaa |
| 008 |
121227s1979 gw | s |||| 0|eng d |
| 020 |
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|a 9783642671883
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| 024 |
7 |
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|a 10.1007/978-3-642-67188-3
|2 doi
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| 040 |
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|a Sistema de Bibliotecas del Tecnológico de Costa Rica
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| 100 |
1 |
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|a Gladtke, Erich.
|e author.
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| 245 |
1 |
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|a Pharmacokinetics
|b An Introduction /
|c by Erich Gladtke, Hans Michael von Hattingberg.
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| 250 |
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|a 1st ed. 1979.
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| 260 |
# |
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|a Berlin, Heidelberg :
|b Springer Berlin Heidelberg :
|b Imprint: Springer,
|c 1979.
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| 300 |
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|a XII, 144 p. 5 illus.
|b online resource.
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| 336 |
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|a text
|b txt
|2 rdacontent
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| 337 |
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|a computer
|b c
|2 rdamedia
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| 338 |
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|a online resource
|b cr
|2 rdacarrier
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| 505 |
0 |
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|a I. Volume of Distribution -- II. Compartments -- 1. Protein Binding -- 2. Gastrointestinal Reabsorption -- III. Elimination -- 1. Equation for Elimination -- IV. Steady State -- 1. Conditions for a Steady State -- 2. Artificial Steady State — Continous Infusion -- V. Multicompartment Systems -- 1. The Model -- 2. Dost’s Principle of Corresponding Areas -- 3. Dost’s Rule of Corresponding Fractional Areas -- 4. General Consideration of Multicompartment Models -- VI. Pharmacokinetics and Treatment -- 1. Repeated Administration of a Drug -- VII. Pharmacokinetics of Gastrointestinal Absorption -- 1. Gastrointestinal Absorption and the Bateman Function -- 2. Reconstruction of the Invasion Curves -- 3. Use of the Invasion Curves -- 4. Calculation of Dose-Proportional Absorption -- 5. Variants of the Invasion Process in Gastrointestinal Absorption -- 6. Conclusions -- 7. Appendix: Some Formulae and Their Derivation -- VIII. Interaction -- 1 Elimination -- 2. Volume of Distribution -- 3. Conclusions -- IX. Use of Analogue Computers in Pharmacokinetics -- 1. Principle of the Analogue Computer -- 2. Programming the Analogue Computer -- 3. Use -- X. Practical Application of Pharmacokinetic Procedures -- 1. Methods of Measurement -- 2. Assessment of the Results of Animal Experiments -- 3. Derivation of Pharmacokinetic Parameters and Constants -- 4. Mathematical Basis of Programming -- 5. Examples of Calculation -- Further Reading.
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| 650 |
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|a Pharmacology.
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| 650 |
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|a Pharmacy.
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| 650 |
1 |
4 |
|a Pharmacology/Toxicology.
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| 650 |
2 |
4 |
|a Pharmacy.
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| 700 |
1 |
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|a Hattingberg, Hans Michael von.
|e author.
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| 710 |
2 |
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|a SpringerLink (Online service)
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| 773 |
0 |
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|t Springer eBooks
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| 856 |
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|u https://doi.org/10.1007/978-3-642-67188-3
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