The Practice of Peptide Synthesis

The Practice of Peptide Synthesis

Detalles Bibliográficos
Autores principales: Bodanszky, Miklos. (Autor), Bodanszky, Agnes. (Autor)
Autor Corporativo: SpringerLink (Online service)
Formato: eBook
Lenguaje:English
Publicado: Berlin, Heidelberg : Springer Berlin Heidelberg : Imprint: Springer, 1994.
Edición:2nd ed. 1994.
Colección:Springer Lab Manuals
Materias:
Biochemistry.
Organic chemistry.
Biochemistry, general.
Organic Chemistry.
Acceso en línea:https://doi.org/10.1007/978-3-642-85055-4
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024 7 |a 10.1007/978-3-642-85055-4  |2 doi 
040 |a Sistema de Bibliotecas del Tecnológico de Costa Rica 
100 1 |a Bodanszky, Miklos.  |e author. 
245 1 4 |a The Practice of Peptide Synthesis  |c by Miklos Bodanszky, Agnes Bodanszky. 
250 |a 2nd ed. 1994. 
260 # # |a Berlin, Heidelberg :  |b Springer Berlin Heidelberg :  |b Imprint: Springer,  |c 1994. 
300 |a XVIII, 217 p. 41 illus.  |b online resource. 
336 |a text  |b txt  |2 rdacontent 
337 |a computer  |b c  |2 rdamedia 
338 |a online resource  |b cr  |2 rdacarrier 
490 1 |a Springer Lab Manuals 
505 0 |a I Introduction -- II Protecting Groups -- 1 Introduction of Amine Protecting Groups -- 2 Blocking of the ?-Carboxyl Group -- 3 Protection of Side Chain Functions -- III Activation and Coupling -- 1 The Acid Chloride Procedure -- 2 The Azide Process -- 3 Symmetrical Anhydrides -- 4 Mixed Anhydrides -- 5 Preparation of Active Esters -- 6 Coupling with Active Esters -- 7 Peptide Bond Formation with the Aid of Coupling Reagents -- IV Removal of Protecting Groups -- 1 Hydrogenation -- 2 Reduction with Sodium in Liquid Ammonia -- 3 Removal of the Phthalyl (Phthaloyl) Group by Hydrazinolysis -- 4 Acidolysis -- 5 Hydrolysis -- 6 Base Catalyzed Elimination -- 7 Nucleophilic Displacement -- 8 Iodolysis -- 9 Reduction of Methionine Sulfoxide Containing Peptides -- V Special Procedures -- 1 Ammonolysis of Esters -- 2 Transesterification -- 3 Cyclization -- 4 Polycondensation -- 5 Partial Synthesis -- VI Models for the Study of Racemization -- 1 Benzoyl-leucyl-glycine Ethyl Ester -- 2 The Anderson-Callahan Test -- 3 Acylation with Acetyl-l-isoleucine -- 4 The Izumiya-Muraoka Model -- 5 Synthesis and Enantioselective Enzymic Hydrolysis of Tetraalanine -- VII Reagents for Peptide Synthesis -- 1 tert-Butyl Azidoformate -- 2 1-Adamantyl Chlorocarbonate -- 3 1-Isobutyloxycarbonyl-2-isobutyloxy-1,2-dihydroquinoline (IIDQ) -- 4 Diphenyl Phosphorazidate (Diphenylphosphoryl Azide, DPPA) -- 5 3-Hydroxy-3,4-dihydroquinazoline-4-one (4-Hydroxyquinazoline 3-oxide) -- 6 1-Hydroxybenzotriazole -- 7 Ethyl 2-hydroximino-2-cyanoacetate -- 8 1-Guanyl-3,5-dimethyl-pyrazole Nitrate -- VIII Appendix -- 1 Conversion of Dicyclohexylammonium Salts of Protected Amino Acids to the Free Acids -- 2 Preparation pf Analytical Samples. 
650 0 |a Biochemistry. 
650 0 |a Organic chemistry. 
650 1 4 |a Biochemistry, general. 
650 2 4 |a Organic Chemistry. 
700 1 |a Bodanszky, Agnes.  |e author. 
710 2 |a SpringerLink (Online service) 
773 0 |t Springer eBooks 
856 4 0 |u https://doi.org/10.1007/978-3-642-85055-4 

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