Systems Biological Approaches in Infectious Diseases

Bibliographic Details
Corporate Author: SpringerLink (Online service)
Other Authors: Boshoff, Helena I. (Editor), Barry, Clifton E. (Editor)
Format: eBook
Language:English
Published: Basel : Birkhäuser Basel : Imprint: Birkhäuser, 2007.
Edition:1st ed. 2007.
Series:Progress in Drug Research, 64
Subjects:
Online Access:https://doi.org/10.1007/978-3-7643-7567-6
Table of Contents:
  • Systems biology and its impact on anti-infective drug development
  • Applications of transcriptional profiling in antibiotics discovery and development
  • Chemical genetics: An evolving toolbox for target identification and lead optimization
  • Proteomic profiling of cellular stresses in Bacillus subtilis reveals cellular networks and assists in elucidating antibiotic mechanisms of action
  • Elucidating the mode-of-action of compounds from metabolite profiling studies
  • A subsystems-based approach to the identification of drug targets in bacterial pathogens
  • Metabolic control analysis to identify optimal drug targets
  • The protein network as a tool for finding novel drug targets
  • Toxicogenomics applied to predictive and exploratory toxicology for the safety assessment of new chemical entities: a long road with deep potholes
  • Biological robustness in complex host-pathogen systems
  • Toward whole cell modeling and simulation: Comprehensive functional genomics through the constraint-based approach
  • Genomics of host-pathogen interactions.