Molecular, Clinical and Environmental Toxicology Volume 1: Molecular Toxicology /
| Autor Corporativo: | |
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| Otros Autores: | |
| Formato: | eBook |
| Lenguaje: | English |
| Publicado: |
Basel :
Birkhäuser Basel : Imprint: Birkhäuser,
2009.
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| Edición: | 1st ed. 2009. |
| Colección: | Experientia Supplementum,
99 |
| Materias: | |
| Acceso en línea: | https://doi.org/10.1007/978-3-7643-8336-7 |
Tabla de Contenidos:
- Historical milestones and discoveries that shaped the toxicology sciences
- Physiologically based toxicokinetic models and their application in human exposure and internal dose assessment
- The role of biotransformation and bioactivation in toxicity
- Genotoxicity: damage to DNA and its consequences
- Role of DNA repair in the protection against genotoxic stress
- On the impact of the molecule structure in chemical carcinogenesis
- Chemical induced alterations in p53 signaling
- Molecular pathways involved in cell death after chemically induced DNA damage
- The aryl hydrocarbon receptor at the crossroads of multiple signaling pathways
- Mapping the epigenome — impact for toxicology
- Receptors mediating toxicity and their involvement in endocrine disruption
- Toxicogenomics: transcription profiling for toxicology assessment
- The role of toxicoproteomics in assessing organ specific toxicity
- High-throughput screening for analysis of in vitro toxicity.