Molecular, Clinical and Environmental Toxicology Volume 1: Molecular Toxicology /
| Corporate Author: | |
|---|---|
| Other Authors: | |
| Format: | eBook |
| Language: | English |
| Published: |
Basel :
Birkhäuser Basel : Imprint: Birkhäuser,
2009.
|
| Edition: | 1st ed. 2009. |
| Series: | Experientia Supplementum,
99 |
| Subjects: | |
| Online Access: | https://doi.org/10.1007/978-3-7643-8336-7 |
Table of Contents:
- Historical milestones and discoveries that shaped the toxicology sciences
- Physiologically based toxicokinetic models and their application in human exposure and internal dose assessment
- The role of biotransformation and bioactivation in toxicity
- Genotoxicity: damage to DNA and its consequences
- Role of DNA repair in the protection against genotoxic stress
- On the impact of the molecule structure in chemical carcinogenesis
- Chemical induced alterations in p53 signaling
- Molecular pathways involved in cell death after chemically induced DNA damage
- The aryl hydrocarbon receptor at the crossroads of multiple signaling pathways
- Mapping the epigenome - impact for toxicology
- Receptors mediating toxicity and their involvement in endocrine disruption
- Toxicogenomics: transcription profiling for toxicology assessment
- The role of toxicoproteomics in assessing organ specific toxicity
- High-throughput screening for analysis of in vitro toxicity.