Novel T cell receptors reactive to the HPV16 E6 and E7 oncoproteins and strategy to potentiate their signaling strength using a co-stimulatory chimeric antigen receptor /
More than 95% of all cervical cancer cases worldwide are caused by high-risk human papillomaviruses (HPV). The transformation and survival of the malignant HPV+ cells depend on the expression of the viral E6 and E7 oncoproteins, which makes them appropriate tumor-specific targets for immunotherapy....
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| Format: | Thesis Book |
| Language: | English |
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Heidelberg, [Alemania],
2023.
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