|
|
|
|
| LEADER |
03240nam a22003015i 4500 |
| 001 |
000276838 |
| 005 |
20200921145650.0 |
| 007 |
cr nn 008mamaa |
| 008 |
180908s2018 xxu| s |||| 0|eng d |
| 020 |
|
|
|a 9781493986484
|
| 024 |
7 |
|
|a 10.1007/978-1-4939-8648-4
|2 doi
|
| 040 |
|
|
|a Sistema de Bibliotecas del Tecnológico de Costa Rica
|
| 245 |
1 |
0 |
|a Antibody Engineering :
|b Methods and Protocols /
|c edited by Damien Nevoltris, Patrick Chames.
|
| 250 |
|
|
|a 3rd ed. 2018.
|
| 260 |
# |
# |
|a New York, NY :
|b Springer New York :
|b Imprint: Humana,
|c 2018.
|
| 300 |
|
|
|a XVI, 543 p. 106 illus., 73 illus. in color. :
|b online resource.
|
| 336 |
|
|
|a text
|b txt
|2 rdacontent
|
| 337 |
|
|
|a computer
|b c
|2 rdamedia
|
| 338 |
|
|
|a online resource
|b cr
|2 rdacarrier
|
| 490 |
1 |
|
|a Methods in Molecular Biology,
|v 1827
|
| 505 |
0 |
|
|a Antibody Design and Humanization via In Silico Modeling -- Antibody Affinity Maturation by Computational Design -- Use of IMGT® Databases and Tools for Antibody Engineering and Humanization -- Construction of Human Naïve Antibody Gene Libraries -- Construction of Synthetic Antibody Libraries -- Construction of Histidine-Enriched Shark IgNAR Variable Domain Antibody Libraries for the Isolation of pH-Sensitive vNAR Fragments -- Display Technologies for Generation of Ig Single Variable Domains -- A Streamlined Approach for the Construction of Large Yeast Surface Display Fab Antibody Libraries -- Phage Display and Selections on Purified Antigens -- Selection of Antibodies to Transiently Expressed Membrane Proteins Using Phage Display -- Selection of Antibody Fragments against Structured DNA by Phage Display -- Selection of Antibody Fragments by Yeast Display -- Rapid Selection of High Affinity Antibody scFv Fragments Using Ribosome Display -- In Vitro Selection of Single Domain Antibody (VHH) Using cDNA Display -- Sequencing and Affinity Determination of Antigen-Specific B Lymphocytes from Peripheral Blood -- Expression of IgG Monoclonals with Engineered Immune Effector Functions -- An IRES-Mediated Tricistronic Vector for Efficient Generation of Stable, High Level Monoclonal Antibody Producing CHO DG44 Cell Lines -- Production, Purification, and Characterization of Antibody-TNF Superfamily Ligand Fusion Proteins -- Chemoenzymatic Defucosylation of Therapeutic Antibodies for Enhanced Effector Functions Using Bacterial α-Fucosidases -- Fc Glyco- and Fc Protein-Engineering: Design of Antibody Variants with Improved ADCC and CDC Activity -- Fc Engineering: Tailored Synthetic Human IgG1-Fc Repertoire for High Affinity Interaction with FcRn at pH 6.0 -- Measuring Antibody-Antigen Binding Kinetics Using Surface Plasmon Resonance -- Parallel Evolution of Antibody Affinity and Thermal Stability for Optimal Biotherapeutic Development -- The Use of Somatic Hypermutation for the Affinity Maturation of Therapeutic Antibodies -- Selection and Use of Intracellular Antibodies -- Site-Specific Radioactive Labeling of Nanobodies.
|
| 650 |
|
0 |
|a Immunology.
|
| 650 |
1 |
4 |
|a Immunology.
|
| 700 |
1 |
|
|a Nevoltris, Damien.
|e editor.
|
| 700 |
1 |
|
|a Chames, Patrick.
|e editor.
|
| 710 |
2 |
|
|a SpringerLink (Online service)
|
| 773 |
0 |
|
|t Springer eBooks
|
| 900 |
|
|
|a Libro descargado a ALEPH en bloque (proveniente de proveedor)
|