|
|
|
|
| LEADER |
03907nam a22002895i 4500 |
| 001 |
000278468 |
| 005 |
20210630152646.0 |
| 007 |
cr nn 008mamaa |
| 008 |
101109s2011 xxu| s |||| 0|eng d |
| 020 |
|
|
|a 9781607619192
|
| 024 |
7 |
|
|a 10.1007/978-1-60761-919-2
|2 doi
|
| 040 |
|
|
|a Sistema de Bibliotecas del Tecnológico de Costa Rica
|
| 245 |
1 |
0 |
|a Cell-Penetrating Peptides :
|b Methods and Protocols /
|c edited by Ülo Langel.
|
| 250 |
|
|
|a 1st ed. 2011.
|
| 260 |
# |
# |
|a Totowa, NJ :
|b Humana Press :
|b Imprint: Humana,
|c 2011.
|
| 300 |
|
|
|a XV, 586 p. 108 illus., 4 illus. in color. :
|b online resource.
|
| 336 |
|
|
|a text
|b txt
|2 rdacontent
|
| 337 |
|
|
|a computer
|b c
|2 rdamedia
|
| 338 |
|
|
|a online resource
|b cr
|2 rdacarrier
|
| 490 |
1 |
|
|a Methods in Molecular Biology,
|v 683
|
| 505 |
0 |
|
|a Classes and prediction of cell-penetrating peptides -- Penetratin story : an overview -- Testing membrane interactions of CPPs -- Interactions of amphipathic CPPs with model membranes -- NMR studies of three-dimensional structure and positioning of CPPs in membrane model systems -- Measurements of the intracellular stability of CPPs -- Tools for predicting binding and insertion of CPPs into lipid bilayers -- Studies of proteoglycan involvement in CPP-mediated delivery -- Uptake Kinetics of cell-penetrating peptides -- Thermodynamics of lipid interactions with cell-penetrating peptides -- Calcium and membrane repair -- Mapping of protein transduction pathways with fluorescent microscopy -- Insight into cell-entry mechanisms of CPPs by electron microscopy -- Toxicity methods for CPPs -- Comparison of CPP uptake methods -- Characterization of cellular internalization pathways for CPP-mediated oligonucleotide delivery -- Mimicry of protein function with cell-penetrating peptides -- Homeoprotein intercellular transfer, the hidden face of cell-penetrating peptides -- Pharmacology, biodistribution, and efficacy of GPCR-based pepducins in disease models -- Identification and Characterization of Tissue-Specific Protein Transduction Domains using Peptide Phage Display -- Applications of Cell Penetrating Peptides as Signal Transduction Modulators for the Selective Induction of Apoptosis -- Splice Redirection as a Convenient Assay to Monitor CPP-ON Efficiency and Mechanism -- CPP directed oligonucleotide exon skipping in animal models of Duchenne muscular dystrophy -- PTD-DRBD siRNA delivery -- A non-covalent peptide-based strategy for siRNA delivery -- Application of PepFect peptides for the delivery of splice correcting oligonucleotides -- Internalization of nucleoside phosphates into live cells by complex formation with different CPPs and JBS-Nucleoducin -- Enhanced cellular delivery of cell-penetrating peptide –peptide nucleic acid conjugates by photochemical internalization (PCI) -- Identification of homing peptides using the in vivo phage display technology -- Measuring the action of CPP-siRNA conjugates in the lung -- Intracellular delivery of nanoparticles with CPPs -- Multifunctional CPP polymer system for tumor-targeted pDNA and siRNA delivery -- Cell Penetrating Penta-Peptides (CPP5s) and Bax Inhibiting Peptides (BIPs): Protocol for their application -- PAIR technology: exon-specific RNA binding protein isolation in live cells -- Quantitation of cellular and topical uptake of luciferin oligoarginine conjugates -- Industrial-scale manufacturing of a possible oligonucleotide cargo CPP based drug -- Application of a fusiogenic peptide GALA for intracellular delivery -- Therapeutic Applications of Cell-Penetrating Peptides -- Nonclinical and clinical experiences with CPP-based self assembling peptide systems in topical drug development.
|
| 650 |
|
0 |
|a Cell biology.
|
| 650 |
1 |
4 |
|a Cell Biology.
|
| 700 |
1 |
|
|a Langel, Ülo.
|e editor.
|
| 710 |
2 |
|
|a SpringerLink (Online service)
|
| 773 |
0 |
|
|t Springer eBooks
|
| 900 |
|
|
|a Libro descargado a ALEPH en bloque (proveniente de proveedor)
|