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100301s2009 xxu| s |||| 0|eng d |
| 020 |
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|a 9781603273350
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| 024 |
7 |
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|a 10.1007/978-1-60327-335-0
|2 doi
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| 040 |
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|a Sistema de Bibliotecas del Tecnológico de Costa Rica
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| 245 |
1 |
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|a Functional Selectivity of G Protein-Coupled Receptor Ligands :
|b New Opportunities for Drug Discovery /
|c edited by Kim Neve.
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| 250 |
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|a 1st ed. 2009.
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| 260 |
# |
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|a Totowa, NJ :
|b Humana Press :
|b Imprint: Humana,
|c 2009.
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| 300 |
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|a X, 226 p. 29 illus., 3 illus. in color. :
|b online resource.
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| 336 |
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|a text
|b txt
|2 rdacontent
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| 337 |
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|a computer
|b c
|2 rdamedia
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| 338 |
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|a online resource
|b cr
|2 rdacarrier
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| 490 |
1 |
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|a The Receptors,
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| 505 |
0 |
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|a Theoretical and Mechanistic Aspects of Functional Selectivity -- Historical Overview of the Concept of Functional Selectivity -- Functional Selectivity: Theoretical Considerations and Future Directions -- Agonist-Selective Coupling of G Protein-Coupled Receptors -- Ligand-Selective Receptor Desensitization and Endocytosis -- Selectivity for G Protein or Arrestin-Mediated Signaling -- In Vivo Evidence for and Consequences of Functional Selectivity -- Subfamilies of Therapeutically Relevant Receptors -- Functional Selectivity at Adrenergic Receptors -- Signaling Diversity Mediated by Muscarinic Acetylcholine Receptor Subtypes and Evidence for Functional Selectivity -- Functional Selectivity at Serotonin Receptors -- Functional Selectivity at Dopamine Receptors -- Functional Selectivity at Receptors for Cannabinoids and Other Lipids -- Functional Selectivity at Opioid Receptors -- Functional Selectivity at Non-Opioid Peptide Receptors.
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| 650 |
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0 |
|a Neurosciences.
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| 650 |
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0 |
|a Pharmacology.
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| 650 |
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0 |
|a Neurobiology.
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| 650 |
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0 |
|a Neurology .
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| 650 |
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0 |
|a Human physiology.
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| 650 |
1 |
4 |
|a Neurosciences.
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| 650 |
2 |
4 |
|a Pharmacology/Toxicology.
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| 650 |
2 |
4 |
|a Neurobiology.
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| 650 |
2 |
4 |
|a Neurology.
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| 650 |
2 |
4 |
|a Human Physiology.
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| 700 |
1 |
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|a Neve, Kim.
|e editor.
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| 710 |
2 |
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|a SpringerLink (Online service)
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| 773 |
0 |
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|t Springer eBooks
|