Functional Selectivity of G Protein-Coupled Receptor Ligands : New Opportunities for Drug Discovery /
Autor Corporativo: | |
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Otros Autores: | |
Formato: | eBook |
Lenguaje: | English |
Publicado: |
Totowa, NJ :
Humana Press : Imprint: Humana,
2009.
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Edición: | 1st ed. 2009. |
Colección: | The Receptors,
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Materias: |
Tabla de Contenidos:
- Theoretical and Mechanistic Aspects of Functional Selectivity
- Historical Overview of the Concept of Functional Selectivity
- Functional Selectivity: Theoretical Considerations and Future Directions
- Agonist-Selective Coupling of G Protein-Coupled Receptors
- Ligand-Selective Receptor Desensitization and Endocytosis
- Selectivity for G Protein or Arrestin-Mediated Signaling
- In Vivo Evidence for and Consequences of Functional Selectivity
- Subfamilies of Therapeutically Relevant Receptors
- Functional Selectivity at Adrenergic Receptors
- Signaling Diversity Mediated by Muscarinic Acetylcholine Receptor Subtypes and Evidence for Functional Selectivity
- Functional Selectivity at Serotonin Receptors
- Functional Selectivity at Dopamine Receptors
- Functional Selectivity at Receptors for Cannabinoids and Other Lipids
- Functional Selectivity at Opioid Receptors
- Functional Selectivity at Non-Opioid Peptide Receptors.