Experimental Cholestasis Research /

Detalles Bibliográficos
Autor Corporativo: SpringerLink (Online service)
Otros Autores: Vinken, Mathieu. (Editor )
Formato: eBook
Lenguaje:English
Publicado: New York, NY : Springer New York : Imprint: Humana, 2019.
Edición:1st ed. 2019.
Colección:Methods in Molecular Biology, 1981
Materias:
Tabla de Contenidos:
  • Mechanisms of Drug-Induced Cholestasis
  • LC-MS/MS Analysis of Bile Acids in In Vitro Samples
  • Pipe-3D: A Pipeline Based on Immunofluorescence, 3D Confocal Imaging, Reconstructions, and Morphometry for Biliary Network Analysis in Cholestasis
  • Vesicle-Based and Hepatocyte-Based Assays for Identification of Drug Candidates Inhibiting BSEP Function
  • The C-DILI™ Assay: An Integrated In Vitro Approach to Predict Cholestatic Hepatotoxicity
  • In Vivo Measurement of Hepatic Drug Transporter Inhibition with Radiolabeled Bile Acids
  • Measuring the Impact of Bile Acids on the Membrane Order of Primary Hepatocytes and Isolated Mitochondria by Fluorescence Imaging and Spectroscopy
  • The Role and Study of Mitochondrial Impairment and Oxidative Stress in Cholestasis
  • Measuring Apoptosis and Necrosis in Cholestatic Liver Injury
  • Necrosome Formation and Necroptosis in Experimental Cholestasis
  • Proteomics in Primary Biliary Cholangitis
  • Transcriptomics Analysis of Cholestatic Compounds In Vitro
  • Systems Microscopy of Stress Response Pathways in Cholestasis Research
  • Mouse Models for Diseases in the Cholangiocyte Lineage
  • Common Bile Duct Ligation as Model for Secondary Biliary Cirrhosis
  • 3,5-Diethoxycarbonyl-1,4-Dihydrocollidine Diet: A Rodent Model in Cholestasis Research
  • A Rotavirus-Induced Mouse Model to Study Biliary Atresia and Neonatal Cholestasis
  • Zebrafish as a Model to Study Cholestatic Liver Diseases
  • Set-Up and Use of HepaRG Cells in Cholestasis Research
  • Organotypic 3D HepaRG Liver Model for Assessment of Drug-Induced Cholestasis
  • Establishment of Sandwich Cultures of Primary Human Hepatocytes
  • Detection of Drug-Induced Cholestasis Potential in Sandwich-Cultured Human Hepatocytes
  • Ex Vivo Model in Cholestasis Research
  • Patient-Derived Organoids from Human Bile: An In Vitro Method to Study Cholangiopathies
  • Use of Biliary Organoids in Cholestasis Research
  • In Silico Approaches to Predict Drug-Transporter Interaction Profiles: Data Mining, Model Generation, and Link to Cholestasis.