|
|
|
|
| LEADER |
03275nam a22003135i 4500 |
| 001 |
000281976 |
| 005 |
20210416094832.0 |
| 007 |
cr nn 008mamaa |
| 008 |
130321s2013 xxu| s |||| 0|eng d |
| 020 |
|
|
|a 9781627033213
|
| 024 |
7 |
|
|a 10.1007/978-1-62703-321-3
|2 doi
|
| 040 |
|
|
|a Sistema de Bibliotecas del Tecnológico de Costa Rica
|
| 245 |
1 |
0 |
|a Cytochrome P450 Protocols /
|c edited by Ian R. Phillips, Elizabeth A. Shephard, Paul R. Ortiz de Montellano.
|
| 250 |
|
|
|a 3rd ed. 2013.
|
| 260 |
# |
# |
|a Totowa, NJ :
|b Humana Press :
|b Imprint: Humana,
|c 2013.
|
| 300 |
|
|
|a XII, 319 p. 53 illus., 31 illus. in color. :
|b online resource.
|
| 336 |
|
|
|a text
|b txt
|2 rdacontent
|
| 337 |
|
|
|a computer
|b c
|2 rdamedia
|
| 338 |
|
|
|a online resource
|b cr
|2 rdacarrier
|
| 490 |
1 |
|
|a Methods in Molecular Biology,
|
| 505 |
0 |
|
|a Bioluminescent Assays for Cytochrome P450 Enzymes. In Vitro Drug-Drug Interaction Assay -- High-Throughput Mass Spectrometric Cytochrome P450 Inhibition Screening -- The Synthesis, Characterization and Application of 13C-Methyl Isocyanide as an NMR Probe of Heme Protein Active Sites -- High-Throughput Fluorescence Assay for Cytochrome P450 Mechanism-Based Inactivators -- Identification of Endogenous Substrates of Orphan Cytochrome P450 Enzymes Through the Use of Untargeted Metabolomics Approaches -- Genetic and Mass Spectrometric Tools for Elucidating the Physiological Function(s) of Cytochrome P450 Enzymes from Mycobacterium Tuberculosis -- An Escherichia coli Expression-Based Approach for Porphyrin Substitution in Heme Proteins -- Expression in Escherichia coli of a Cytochrome P450 Enzyme with a Cobalt Protoporphyrin IX Prosthetic Group -- Nanodiscs in the Studies of Membrane-Bound Cytochrome P450 Enzymes -- Rapid LC-MS Drug Metabolite Profiling Using Bioreactor Particles -- Fluorescence-Based Screening of cytochrome P450 activities in Intact Cells -- Screening for Cytochrome P450 Reactivity with a Reporter Enzyme -- High-Throughput Fluorescence Assay of Cytochrome P450 3A4 -- Targeted Protein Capture for Analysis of Electrophile-Protein Adducts -- DNA Shuffling of Cytochrome P450 Enzymes -- Measurement of P450 Difference Spectra Using Intact Cells -- DNA Shuffling of Cytochromes P450 for Indigoid Pigment Production -- P450 oxidoreductase – Genotyping, Expression, Purification of Recombinant Protein and Activity Assessments of Wild-Type and Mutant Protein -- LICRED: A Versatile Drop-In Vector for Rapid Generation of Redox-Self-Sufficient Cytochromes P450 -- Update on Allele Nomenclature for Human Cytochromes P450 and the Human Cytochrome P450 Allele (CYP-allele) Nomenclature Database -- Simultaneous in vivo Phenotyping of CYP Enzymes -- Detection of Regulatory Polymorphisms: High-Throughput Capillary DNase-I Footprinting -- Isolation of Mouse Hepatocytes -- Highly Efficient SiRNA and Gene Transfer into Hepatocyte-like HepaRG Cells and Primary Human Hepatocytes: New Means for Drug Metabolism and Toxicity Studies.
|
| 650 |
|
0 |
|a Proteins .
|
| 650 |
1 |
4 |
|a Protein Science.
|
| 650 |
2 |
4 |
|a Protein-Ligand Interactions.
|
| 700 |
1 |
|
|a Phillips, Ian R.
|e editor.
|
| 700 |
1 |
|
|a Shephard, Elizabeth A.
|e editor.
|
| 700 |
1 |
|
|a Ortiz de Montellano, Paul R.
|e editor.
|
| 710 |
2 |
|
|a SpringerLink (Online service)
|
| 773 |
0 |
|
|t Springer eBooks
|