Membrane Transporters in Drug Discovery and Development : Methods and Protocols /

Detalles Bibliográficos
Autor Corporativo: SpringerLink (Online service)
Otros Autores: Yan, Qing. (Editor )
Formato: eBook
Lenguaje:English
Publicado: Totowa, NJ : Humana Press : Imprint: Humana, 2010.
Edición:1st ed. 2010.
Colección:Methods in Molecular Biology, 637
Materias:
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020 |a 9781607617006 
024 7 |a 10.1007/978-1-60761-700-6  |2 doi 
040 |a Sistema de Bibliotecas del Tecnológico de Costa Rica 
245 1 0 |a Membrane Transporters in Drug Discovery and Development :  |b Methods and Protocols /  |c edited by Qing Yan. 
250 |a 1st ed. 2010. 
260 # # |a Totowa, NJ :  |b Humana Press :  |b Imprint: Humana,  |c 2010. 
300 |a XIII, 357 p. 60 illus., 2 illus. in color. :  |b online resource. 
336 |a text  |b txt  |2 rdacontent 
337 |a computer  |b c  |2 rdamedia 
338 |a online resource  |b cr  |2 rdacarrier 
490 1 |a Methods in Molecular Biology,  |v 637 
505 0 |a Membrane Transporters and Drug Development: Relevance to Pharmacogenomics, Nutrigenomics, Epigenetics, and Systems Biology -- Bioinformatics for Transporter Pharmacogenomics and Systems Biology: Data Integration and Modeling with UML -- Multidrug Resistance: Phylogenetic Characterization of Superfamilies of Secondary Carriers that Include Drug Exporters -- Targeting Drug Transporters – Combining In Silico and In Vitro Approaches to Predict In Vivo -- Methods to Evaluate Transporter Activity in Cancer -- Analysis of Expression of Drug Resistance-Linked ABC Transporters in Cancer Cells by Quantitative RT-PCR -- Fluorescence Studies of Drug Binding and Translocation by Membrane Transporters -- A Model for Transport Studies of the Blood–Brain Barrier -- Genetic Variants in the Vesicular Monoamine Transporter 1 (VMAT1/SLC18A1) and Neuropsychiatric Disorders -- Equilibrium Binding and Transport by Vesicular Acetylcholine Transporter -- ABC Transporters in Ophthalmic Disease -- Imaging of Protein Translocation In Situ in Skeletal Muscle of Living Mice -- Glucose Transporters in Parasitic Protozoa -- NMR Studies of Membrane Proteins -- Site-Directed Mutagenesis in the Study of Membrane Transporters -- Xenopus laevis Oocytes -- Measurement of Intracellular pH -- Measurement of Plasma Membrane Calcium–Calmodulin-Dependent ATPase (PMCA) Activity -- Assessment of the Contribution of the Plasma Membrane Calcium ATPase, PMCA, Calcium Transporter to Synapse Function Using Patch Clamp Electrophysiology and Fast Calcium Imaging. 
650 0 |a Human physiology. 
650 0 |a Pharmacology. 
650 0 |a Cell membranes . 
650 1 4 |a Human Physiology. 
650 2 4 |a Pharmacology/Toxicology. 
650 2 4 |a Membrane Biology. 
700 1 |a Yan, Qing.  |e editor. 
710 2 |a SpringerLink (Online service) 
773 0 |t Springer eBooks 
900 |a Libro descargado a ALEPH en bloque (proveniente de proveedor)