Membrane Transporters in Drug Discovery and Development : Methods and Protocols /
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| Format: | eBook |
| Language: | English |
| Published: |
Totowa, NJ :
Humana Press : Imprint: Humana,
2010.
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| Edition: | 1st ed. 2010. |
| Series: | Methods in Molecular Biology,
637 |
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Table of Contents:
- Membrane Transporters and Drug Development: Relevance to Pharmacogenomics, Nutrigenomics, Epigenetics, and Systems Biology
- Bioinformatics for Transporter Pharmacogenomics and Systems Biology: Data Integration and Modeling with UML
- Multidrug Resistance: Phylogenetic Characterization of Superfamilies of Secondary Carriers that Include Drug Exporters
- Targeting Drug Transporters - Combining In Silico and In Vitro Approaches to Predict In Vivo
- Methods to Evaluate Transporter Activity in Cancer
- Analysis of Expression of Drug Resistance-Linked ABC Transporters in Cancer Cells by Quantitative RT-PCR
- Fluorescence Studies of Drug Binding and Translocation by Membrane Transporters
- A Model for Transport Studies of the Blood-Brain Barrier
- Genetic Variants in the Vesicular Monoamine Transporter 1 (VMAT1/SLC18A1) and Neuropsychiatric Disorders
- Equilibrium Binding and Transport by Vesicular Acetylcholine Transporter
- ABC Transporters in Ophthalmic Disease
- Imaging of Protein Translocation In Situ in Skeletal Muscle of Living Mice
- Glucose Transporters in Parasitic Protozoa
- NMR Studies of Membrane Proteins
- Site-Directed Mutagenesis in the Study of Membrane Transporters
- Xenopus laevis Oocytes
- Measurement of Intracellular pH
- Measurement of Plasma Membrane Calcium-Calmodulin-Dependent ATPase (PMCA) Activity
- Assessment of the Contribution of the Plasma Membrane Calcium ATPase, PMCA, Calcium Transporter to Synapse Function Using Patch Clamp Electrophysiology and Fast Calcium Imaging.