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01946nam a22003495i 4500 |
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131002s2013 xxu| s |||| 0|eng d |
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|a 9781461484127
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7 |
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|a 10.1007/978-1-4614-8412-7
|2 doi
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|a Sistema de Bibliotecas del Tecnológico de Costa Rica
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|a Molecular Pathogenesis of Colorectal Cancer /
|c edited by Kevin M. Haigis, Ph.D.
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250 |
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|a 1st ed. 2013.
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260 |
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|a New York, NY :
|b Springer New York :
|b Imprint: Springer,
|c 2013.
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300 |
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|a VIII, 316 p. 30 illus., 29 illus. in color. :
|b online resource.
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336 |
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|a text
|b txt
|2 rdacontent
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|a computer
|b c
|2 rdamedia
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|a online resource
|b cr
|2 rdacarrier
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|a Preface -- The Genetics of Colorectal Cancer -- Molecular Mechanisms of Colorectal Carcinogenesis -- The association between inflammation and colorectal cancer -- Importance of the niche: Wnt signalling and Stem cell plasticity in intestinal homeostasis and disease -- Mutational activation of KRAS and BRAF in colorectal cancer -- The PI3K pathway in Colorectal Cancers -- TGF-ß signaling pathway and colorectal cancer -- The Clinical Significance of Mutations in Colorectal Cancer -- Colorectal Cancer Genome and Its Implications -- Copy-Number Alterations in the Colorectal Cancer Genome -- Genome-wide association studies in colorectal cancer -- Future prospects for leveraging molecular information in the fight against colorectal cancer -- Index.
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650 |
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|a Cancer research.
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650 |
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|a Molecular biology.
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650 |
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|a Proteins .
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650 |
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|a Cell biology.
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650 |
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|a Cancer Research.
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650 |
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4 |
|a Molecular Medicine.
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650 |
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4 |
|a Protein Science.
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650 |
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4 |
|a Cell Biology.
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700 |
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|a Haigis, Ph.D., Kevin M.
|e editor.
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710 |
2 |
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|a SpringerLink (Online service)
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773 |
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|t Springer eBooks
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900 |
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|a Libro descargado a ALEPH en bloque (proveniente de proveedor)
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