Molecular Pathogenesis of Colorectal Cancer /

Bibliographic Details
Corporate Author: SpringerLink (Online service)
Other Authors: Haigis, Ph.D., Kevin M. (Editor)
Format: eBook
Language:English
Published: New York, NY : Springer New York : Imprint: Springer, 2013.
Edition:1st ed. 2013.
Subjects:
Table of Contents:
  • Preface
  • The Genetics of Colorectal Cancer
  • Molecular Mechanisms of Colorectal Carcinogenesis
  • The association between inflammation and colorectal cancer
  • Importance of the niche: Wnt signalling and Stem cell plasticity in intestinal homeostasis and disease
  • Mutational activation of KRAS and BRAF in colorectal cancer
  • The PI3K pathway in Colorectal Cancers
  • TGF-ß signaling pathway and colorectal cancer
  • The Clinical Significance of Mutations in Colorectal Cancer
  • Colorectal Cancer Genome and Its Implications
  • Copy-Number Alterations in the Colorectal Cancer Genome
  • Genome-wide association studies in colorectal cancer
  • Future prospects for leveraging molecular information in the fight against colorectal cancer
  • Index.