|
|
|
|
| LEADER |
03003nam a22003495i 4500 |
| 001 |
000285333 |
| 005 |
20210518112734.0 |
| 007 |
cr nn 008mamaa |
| 008 |
110621s2011 ne | s |||| 0|eng d |
| 020 |
|
|
|a 9789400714694
|
| 024 |
7 |
|
|a 10.1007/978-94-007-1469-4
|2 doi
|
| 040 |
|
|
|a Sistema de Bibliotecas del Tecnológico de Costa Rica
|
| 100 |
1 |
|
|a Ribatti, Domenico.
|e author.
|
| 245 |
1 |
0 |
|a Mast Cells and Tumours :
|b from Biology to Clinic /
|c by Domenico Ribatti, Enrico Crivellato.
|
| 250 |
|
|
|a 1st ed. 2011.
|
| 260 |
# |
# |
|a Dordrecht :
|b Springer Netherlands :
|b Imprint: Springer,
|c 2011.
|
| 300 |
|
|
|a VIII, 142 p. :
|b online resource.
|
| 336 |
|
|
|a text
|b txt
|2 rdacontent
|
| 337 |
|
|
|a computer
|b c
|2 rdamedia
|
| 338 |
|
|
|a online resource
|b cr
|2 rdacarrier
|
| 505 |
0 |
|
|a Introduction -- 1. The mast cell -- 1.1. A historical overview -- 1.2. Biology of mast cells -- 2. Mast cell mediators -- 2.1. Granule composition -- 2.2. Histamine and serotonin -- 2.3. Proteases -- 2.4. Lipid mediators -- 2.5. Cytokines and growth factors -- 2.6. Chemokines -- 3. The tumour cell -- 3.1. Biology of tumour cell -- 3.2. The importance of microenvironment in tumor metastasis -- 3.3. The “seed and soil” theory -- 4. Tumour angiogenesis -- 4.1. The angiogenic switch -- 4.2. Phenotypic and genotypic characteristics of tumor vessels and genetic evidence that tumours are angiogenesis-dependent -- 4.3. What is the evidence that genetic instability promotes the angiogenic switch? -- 4.4. Hypoxic regulation of tumour angiogenesis -- 4.5. The role of pericytes in tumour angiogenesis -- 4.6. The role of inflammatory cells in tumour angiogenesis -- 4.7. Participation of hematopoietic cells and endothelial precursor cells to tumour angiogenesis -- 4.8. Alternative mechanisms of tumour angiogenesis -- 4.9. Vascular cooption -- 4.10. The prognostic significance of tumour angiogenesis -- 4.11. Angiogenesis is not necessarily involved in tumour progression -- 5. Mast cells and tumours -- 5.1. Mast cells and tumour growth in humans: pro and contra -- 6. Mast cells and tumour angiogenesis -- 6.1. Mast cell-induced angiogenesis studied by means of in vitro and in vivo assays -- 6.2. Mast cell-induced angiogenesis studied by means of experimental carcinogenesis -- 6.3. Angiogenic factors stored in mast cells -- 6.4. Mast cells and angiogenesis in human solid tumours -- 6.5. Mast cells and angiogenesis in human hematological tumours -- 7. Mast cells and tumour lymphangiogenesis -- 8. Drug affecting mast cells -- Concluding remarks and perspectives -- References. .
|
| 650 |
|
0 |
|a Cancer research.
|
| 650 |
|
0 |
|a Oncology .
|
| 650 |
|
0 |
|a Pathology.
|
| 650 |
|
0 |
|a Cell biology.
|
| 650 |
1 |
4 |
|a Cancer Research.
|
| 650 |
2 |
4 |
|a Oncology.
|
| 650 |
2 |
4 |
|a Pathology.
|
| 650 |
2 |
4 |
|a Cell Biology.
|
| 700 |
1 |
|
|a Crivellato, Enrico.
|e author.
|
| 710 |
2 |
|
|a SpringerLink (Online service)
|
| 773 |
0 |
|
|t Springer eBooks
|