High Throughput Screening : Methods and Protocols /

Detalles Bibliográficos
Autor Corporativo: SpringerLink (Online service)
Otros Autores: Janzen, William P. (Editor )
Formato: eBook
Lenguaje:English
Publicado: New York, NY : Springer New York : Imprint: Humana, 2016.
Edición:3rd ed. 2016.
Colección:Methods in Molecular Biology, 1439
Materias:
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245 1 0 |a High Throughput Screening :  |b Methods and Protocols /  |c edited by William P. Janzen. 
250 |a 3rd ed. 2016. 
260 # # |a New York, NY :  |b Springer New York :  |b Imprint: Humana,  |c 2016. 
300 |a XI, 308 p. 101 illus., 71 illus. in color. :  |b online resource. 
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490 1 |a Methods in Molecular Biology,  |v 1439 
505 0 |a Design and Implementation of High Throughput Screening Assays -- Characterization of Inhibitor Binding Through Multiple Inhibitor Analysis: A Novel Local Fitting Method -- High Throughput Screening Using Mass Spectrometry within Drug Discovery -- Structure-Based Virtual Screening of Commercially Available Compound Libraries -- AlphaScreen-Based Assays: Ultra-High Throughput Screening for Small Molecule Inhibitors of Challenging Enzymes and Protein-Protein Interactions -- Instrument Quality Control -- Application of Fluorescence Polarization in HTS Assays -- Time Resolved Fluorescence Assays -- Protein Kinase Selectivity Profiling Using Microfluid Mobility Shift Assays -- Screening for Inhibitors of Kinase Autophosphorylation -- A Fluorescence-Based High Throughput Screening Assay to Identify Growth Inhibitors of the Pathogenic Fungus Aspergillus fumigatus -- Mycobacterium tuberculosis High Throughput Screening -- Identification of State-Dependent Blockers for Voltage Gated Calcium Channels Using a FLIPR Based Assay -- A Luciferase Reporter Gene System for High Throughput Screening of γ-Globin Gene Activators -- A High Throughput Flow Cytometry Assay for Identification of Inhibitors of 3’, 5’-Cyclic Adenosine Monophosphate Efflux -- High Throughput Cell Toxicity Assays -- BRETn: NanoLuc-Based Bioluminescence Resonance Energy Transfer Platform to Monitor Protein-Protein Interactions in Live Cells -- Application of Imaging-Based Assays in Microplate Formats for High Content Screening. 
650 0 |a Biotechnology. 
650 1 4 |a Biotechnology. 
700 1 |a Janzen, William P.  |e editor. 
710 2 |a SpringerLink (Online service) 
773 0 |t Springer eBooks