High Throughput Screening : Methods and Protocols /
| Autor Corporativo: | |
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| Otros Autores: | |
| Formato: | eBook |
| Lenguaje: | English |
| Publicado: |
New York, NY :
Springer New York : Imprint: Humana,
2016.
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| Edición: | 3rd ed. 2016. |
| Colección: | Methods in Molecular Biology,
1439 |
| Materias: |
Tabla de Contenidos:
- Design and Implementation of High Throughput Screening Assays
- Characterization of Inhibitor Binding Through Multiple Inhibitor Analysis: A Novel Local Fitting Method
- High Throughput Screening Using Mass Spectrometry within Drug Discovery
- Structure-Based Virtual Screening of Commercially Available Compound Libraries
- AlphaScreen-Based Assays: Ultra-High Throughput Screening for Small Molecule Inhibitors of Challenging Enzymes and Protein-Protein Interactions
- Instrument Quality Control
- Application of Fluorescence Polarization in HTS Assays
- Time Resolved Fluorescence Assays
- Protein Kinase Selectivity Profiling Using Microfluid Mobility Shift Assays
- Screening for Inhibitors of Kinase Autophosphorylation
- A Fluorescence-Based High Throughput Screening Assay to Identify Growth Inhibitors of the Pathogenic Fungus Aspergillus fumigatus
- Mycobacterium tuberculosis High Throughput Screening
- Identification of State-Dependent Blockers for Voltage Gated Calcium Channels Using a FLIPR Based Assay
- A Luciferase Reporter Gene System for High Throughput Screening of γ-Globin Gene Activators
- A High Throughput Flow Cytometry Assay for Identification of Inhibitors of 3’, 5’-Cyclic Adenosine Monophosphate Efflux
- High Throughput Cell Toxicity Assays
- BRETn: NanoLuc-Based Bioluminescence Resonance Energy Transfer Platform to Monitor Protein-Protein Interactions in Live Cells
- Application of Imaging-Based Assays in Microplate Formats for High Content Screening.