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161019s2017 xxu| s |||| 0|eng d |
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|a 9781493965274
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| 024 |
7 |
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|a 10.1007/978-1-4939-6527-4
|2 doi
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| 040 |
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|a Sistema de Bibliotecas del Tecnológico de Costa Rica
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| 245 |
1 |
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|a HDAC/HAT Function Assessment and Inhibitor Development :
|b Methods and Protocols /
|c edited by Oliver H. Krämer.
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| 250 |
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|a 1st ed. 2017.
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| 260 |
# |
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|a New York, NY :
|b Springer New York :
|b Imprint: Humana,
|c 2017.
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| 300 |
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|a XIV, 415 p. 97 illus., 58 illus. in color. :
|b online resource.
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| 336 |
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|a text
|b txt
|2 rdacontent
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| 337 |
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|a computer
|b c
|2 rdamedia
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| 338 |
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|a online resource
|b cr
|2 rdacarrier
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| 490 |
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|a Methods in Molecular Biology,
|v 1510
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| 505 |
0 |
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|a Detection of Autophagy Induction After HDAC Inhibitor Treatment in Leukemic Cells -- Assessment of HDACi-Induced Protein Cleavage by Caspases -- Assessment of HDACi-Induced Cytotoxicity -- Analysis of HDACi-Induced Changes in Chromosomal Passenger Complex Localization -- Analysis of Histone Deacetylase-Dependent Effects on Cell Migration Using the Stripe Assay -- Using Histone Deacetylase Inhibitors to Analyze the Relevance of HDACs for Translation -- Effects of HDACi on Immunological Functions -- DNA Fiber Spreading Assay to Test HDACi Effects on DNA and Its Replication -- Assessing the Effect of Class I Histone Deacetylase Activity on DNA Double-Strand Break Repair by Homologous Recombination -- Establishment and Characterization of Long-Term Cultures Derived from Primary Acute Myeloid Leukemia Cells for HDAC Inhibitor Research -- Assessing the Histone Deacetylase Activity of SIRT6 in Primary Murine Hepatocytes Via Proximity Ligation Assay -- Purification and Analysis of Male Germ Cells from Adult Mouse Testis -- Generation of Tissue-Specific Mouse Models to Analyze HDAC Functions -- Engineering of Conditional Class I Hdac Knockout Mice and Generation of a Time-Spatial Knockout by a Dual Recombination System -- Xenografting of Cancer Cell Lines for In Vivo Screening of the Therapeutic Potential of HDAC Inhibitors -- Generation of Xenotransplants from Human Cancer Biopsies to Assess Anti-Cancer Activities of HDACi -- Phospho-Flow Analysis of Primary Mouse Cells after HDAC Inhibitor Treatment -- Evaluation of Innate Immune Gene Expression Following HDAC Inhibitor Treatment by High Throughput qPCR and PhosFlow Cytometry -- Assessing HDAC Function in the Regulation of Signal Transducer and Activator of Transcription 5 (STAT5) Activity Using Chromatin Immunoprecipitation (ChIP) -- Modulation of STAT1-Driven Transcriptional Activity by Histone Deacetylases -- Proximity Ligation Assay to Quantify Foxp3 Acetylation in Regulatory T Cells -- Testing the Effects of SIAH Ubiquitin E3 Ligases on Lysine Acetyl Transferases -- Assessment of HDACi-Induced Acetylation of Non-Histone Proteins by Mass Spectrometry -- Assessing the Role of Paralog-Specific Sumoylation of HDAC1 -- Analysis of Histone Deacetylases Sumoylation by Immunoprecipitation Techniques -- How to Distinguish Between the Activity of HDAC1-3 and HDAC6 with Western Blot -- Evaluating the Effect of HDAC8 Inhibition in Malignant Peripheral Nerve Sheath Tumors -- Analyzing the Impact of Pan- and Class-Specific HDACi on Differentiation-Associated Factors -- Encapsulation of the HDACi Ex527 into Liposomes and Polymer-Based Particles -- Preparation of Histone Deacetylase Inhibitor Vorinostat Loaded Poly d, l-lactide-co-glycolide Polymeric Nanoparticles by Nanoprecipitation Method -- Generation and Assessment of Fusions Between HDACi and TKi.
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| 650 |
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|a Proteins .
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| 650 |
1 |
4 |
|a Protein Science.
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| 700 |
1 |
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|a Krämer, Oliver H.
|e editor.
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| 710 |
2 |
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|a SpringerLink (Online service)
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| 773 |
0 |
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|t Springer eBooks
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