HDAC/HAT Function Assessment and Inhibitor Development : Methods and Protocols /
| Autor Corporativo: | |
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| Otros Autores: | |
| Formato: | eBook |
| Lenguaje: | English |
| Publicado: |
New York, NY :
Springer New York : Imprint: Humana,
2017.
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| Edición: | 1st ed. 2017. |
| Colección: | Methods in Molecular Biology,
1510 |
| Materias: |
Tabla de Contenidos:
- Detection of Autophagy Induction After HDAC Inhibitor Treatment in Leukemic Cells
- Assessment of HDACi-Induced Protein Cleavage by Caspases
- Assessment of HDACi-Induced Cytotoxicity
- Analysis of HDACi-Induced Changes in Chromosomal Passenger Complex Localization
- Analysis of Histone Deacetylase-Dependent Effects on Cell Migration Using the Stripe Assay
- Using Histone Deacetylase Inhibitors to Analyze the Relevance of HDACs for Translation
- Effects of HDACi on Immunological Functions
- DNA Fiber Spreading Assay to Test HDACi Effects on DNA and Its Replication
- Assessing the Effect of Class I Histone Deacetylase Activity on DNA Double-Strand Break Repair by Homologous Recombination
- Establishment and Characterization of Long-Term Cultures Derived from Primary Acute Myeloid Leukemia Cells for HDAC Inhibitor Research
- Assessing the Histone Deacetylase Activity of SIRT6 in Primary Murine Hepatocytes Via Proximity Ligation Assay
- Purification and Analysis of Male Germ Cells from Adult Mouse Testis
- Generation of Tissue-Specific Mouse Models to Analyze HDAC Functions
- Engineering of Conditional Class I Hdac Knockout Mice and Generation of a Time-Spatial Knockout by a Dual Recombination System
- Xenografting of Cancer Cell Lines for In Vivo Screening of the Therapeutic Potential of HDAC Inhibitors
- Generation of Xenotransplants from Human Cancer Biopsies to Assess Anti-Cancer Activities of HDACi
- Phospho-Flow Analysis of Primary Mouse Cells after HDAC Inhibitor Treatment
- Evaluation of Innate Immune Gene Expression Following HDAC Inhibitor Treatment by High Throughput qPCR and PhosFlow Cytometry
- Assessing HDAC Function in the Regulation of Signal Transducer and Activator of Transcription 5 (STAT5) Activity Using Chromatin Immunoprecipitation (ChIP)
- Modulation of STAT1-Driven Transcriptional Activity by Histone Deacetylases
- Proximity Ligation Assay to Quantify Foxp3 Acetylation in Regulatory T Cells
- Testing the Effects of SIAH Ubiquitin E3 Ligases on Lysine Acetyl Transferases
- Assessment of HDACi-Induced Acetylation of Non-Histone Proteins by Mass Spectrometry
- Assessing the Role of Paralog-Specific Sumoylation of HDAC1
- Analysis of Histone Deacetylases Sumoylation by Immunoprecipitation Techniques
- How to Distinguish Between the Activity of HDAC1-3 and HDAC6 with Western Blot
- Evaluating the Effect of HDAC8 Inhibition in Malignant Peripheral Nerve Sheath Tumors
- Analyzing the Impact of Pan- and Class-Specific HDACi on Differentiation-Associated Factors
- Encapsulation of the HDACi Ex527 into Liposomes and Polymer-Based Particles
- Preparation of Histone Deacetylase Inhibitor Vorinostat Loaded Poly d, l-lactide-co-glycolide Polymeric Nanoparticles by Nanoprecipitation Method
- Generation and Assessment of Fusions Between HDACi and TKi.