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130622s2013 au | s |||| 0|eng d |
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|a 9783709114100
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| 024 |
7 |
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|a 10.1007/978-3-7091-1410-0
|2 doi
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| 040 |
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|a Sistema de Bibliotecas del Tecnológico de Costa Rica
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| 100 |
1 |
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|a Jakubowski, Hieronim.
|e author.
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| 245 |
1 |
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|a Homocysteine in Protein Structure/Function and Human Disease :
|b Chemical Biology of Homocysteine-containing Proteins /
|c by Hieronim Jakubowski.
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| 250 |
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|a 1st ed. 2013.
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| 260 |
# |
# |
|a Vienna :
|b Springer Vienna :
|b Imprint: Springer,
|c 2013.
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| 300 |
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|a XIII, 166 p. :
|b online resource.
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| 336 |
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|a text
|b txt
|2 rdacontent
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| 337 |
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|a computer
|b c
|2 rdamedia
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| 338 |
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|a online resource
|b cr
|2 rdacarrier
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0 |
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|a 1. Introduction -- 2. Homocysteine. Chemical Synthesis -- Physicochemical Properties -- Quantification Methods -- Metabolic Pathways -- Clinical significance -- 3. Homocysteine Thiolactone -- Chemical Synthesis -- Physicochemical Properties -- Quantification Methods -- Biological Formation and Turnover -- Clinical Significance -- 4. N-Homocysteinylated Proteins -- Functional Consequences -- Albumin -- Fibrinogen -- Cytochrome c -- Other Proteins -- Quantification Methods -- Total N-homocysteinylation assays -- Site-specific N-homocysteinylation assays -- Formation in vivo -- Turnover to Nε-Homocysteinyl-lysine -- Biological Consequences and Clinical Significance -- 5. S-Homocysteinylated Proteins -- Formation in vitro -- Functional Consequences -- Annexin -- Metallothionein -- Fibrilin, Fibronectin, Tropoelastin -- Detection in vivo -- Biological consequences -- Conclusions -- References.
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| 650 |
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|a Proteins .
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| 650 |
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|a Biochemistry.
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| 650 |
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|a Medical biochemistry.
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| 650 |
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|a Metabolic diseases.
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| 650 |
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4 |
|a Protein Structure.
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| 650 |
2 |
4 |
|a Protein Science.
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| 650 |
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4 |
|a Biochemistry, general.
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| 650 |
2 |
4 |
|a Medical Biochemistry.
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| 650 |
2 |
4 |
|a Metabolic Diseases.
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| 710 |
2 |
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|a SpringerLink (Online service)
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| 773 |
0 |
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|t Springer eBooks
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