Homocysteine in Protein Structure/Function and Human Disease : Chemical Biology of Homocysteine-containing Proteins /
| Autor principal: | |
|---|---|
| Autor Corporativo: | |
| Formato: | eBook |
| Lenguaje: | English |
| Publicado: |
Vienna :
Springer Vienna : Imprint: Springer,
2013.
|
| Edición: | 1st ed. 2013. |
| Materias: |
Tabla de Contenidos:
- 1. Introduction
- 2. Homocysteine. Chemical Synthesis
- Physicochemical Properties
- Quantification Methods
- Metabolic Pathways
- Clinical significance
- 3. Homocysteine Thiolactone
- Chemical Synthesis
- Physicochemical Properties
- Quantification Methods
- Biological Formation and Turnover
- Clinical Significance
- 4. N-Homocysteinylated Proteins
- Functional Consequences
- Albumin
- Fibrinogen
- Cytochrome c
- Other Proteins
- Quantification Methods
- Total N-homocysteinylation assays
- Site-specific N-homocysteinylation assays
- Formation in vivo
- Turnover to Nε-Homocysteinyl-lysine
- Biological Consequences and Clinical Significance
- 5. S-Homocysteinylated Proteins
- Formation in vitro
- Functional Consequences
- Annexin
- Metallothionein
- Fibrilin, Fibronectin, Tropoelastin
- Detection in vivo
- Biological consequences
- Conclusions
- References.