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05040nam a22003135i 4500 |
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20210517080007.0 |
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cr nn 008mamaa |
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140312s2014 xxu| s |||| 0|eng d |
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|a 9781627037396
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| 024 |
7 |
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|a 10.1007/978-1-62703-739-6
|2 doi
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| 040 |
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|a Sistema de Bibliotecas del Tecnológico de Costa Rica
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| 245 |
1 |
0 |
|a Molecular Toxicology Protocols /
|c edited by Phouthone Keohavong, Stephen G. Grant.
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| 250 |
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|a 2nd ed. 2014.
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| 260 |
# |
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|a Totowa, NJ :
|b Humana Press :
|b Imprint: Humana,
|c 2014.
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| 300 |
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|a XV, 646 p. 101 illus., 29 illus. in color. :
|b online resource.
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| 336 |
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|a text
|b txt
|2 rdacontent
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| 337 |
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|a computer
|b c
|2 rdamedia
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| 338 |
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|a online resource
|b cr
|2 rdacarrier
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| 490 |
1 |
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|a Methods in Molecular Biology,
|v 1105
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| 505 |
0 |
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|a Array-Based Immunoassays with Rolling-Circle Amplification Detection -- Analysis of Protein Changes Using Two Dimensional Difference Gel Electrophoresis -- Assessment of Pathological and Physiological Changes in Mouse Lung Through Bronchoalveolar Lavage -- Analysis of Clinical and Biological Samples Using Microsphere-Based Multiplexing Luminex System -- Detection of DNA Methylation by MeDIP and MBDCap Assays: An Overview of Techniques -- Screening of DNA Methylation Changes by Methylation-Sensitive Random Amplified Polymorphic DNA-Polymerase Chain Reaction (MS-RAPD-PCR) -- Strategies for Measurement of Biotransformation Enzyme Gene Expression -- Genotyping Technologies: Application to Biotransformation Enzyme Genetic Polymorphism Screening -- TaqMan Fluorogenic Detection System to Analyze Gene Transcription in Autopsy Material -- 32P-Postlabelling Analysis of DNA Adducts -- Modification of the 32P-Postlabeling Method to Detect a Single Adduct Species as a Single Spot -- DNA Isolation and Sample Preparation for Quantitation of Adduct Levels by Accelerator Mass Spectrometry -- Analysis of DNA Strand Cleavage at Abasic Sites -- Premature Chromosome Condensation in Human Resting Peripheral Blood Lymphocytes without Mitogen Stimulation for Chromosome Aberration Analysis Using Specific Whole Chromosome DNA Hybridization Probes -- Mutagen Sensitivity as Measured by Induced Chromatid Breakage as a Marker of Cancer Risk -- Pulsed-Field Gel Electrophoresis Analysis of Multicellular DNA Double-Strand Break Damage and Repair -- Detection of Pig-a Mutant Erythrocytes in the Peripheral Blood of Rats and Mice -- The Blood-Vased Glycophorin A Human In vivo Somatic Mutation Assay -- Flow Cytometric Quantification of Mutant T Cells with Altered Expression of the T-Cell Receptor: Detecting Somatic Mutants in Humans and Mice -- Analysis of in Vivo Mutation at the HPRT and TK Genes of Mouse Lymphocytes -- Quantifying In Vivo Somatic Mutations Using Transgenic Mouse Model Systems -- The Human T-Cell Cloning Assay: Identifying Genotypes Susceptible to Drug Toxicity and Somatic Mutation -- Molecular Analysis of HPRT Mutations in Human Lymphocytes -- Simultaneous Quantification of t(14;18) and HPRT Exon 2/3 Deletions in Human Lymphocytes -- Mutation Screening of the TP53 Gene by Temporal Temperature Gel Electrophoresis -- Detection of Point Mutations of K-ras Oncogene and p53 Tumor Suppressor Gene in Sputum Samples -- ACB-PCR Quantification of Somatic Oncomutations -- Gel-Based Nonradioactive Single Strand Conformational Polymorphism and Mutation Detection -- Detection and Characterization of Oncogene Mutations in Preneoplastic and Early Neoplastic Lesion -- Detection of DNA Double-Strand Breaks and Chromosome Translocations Using Ligation-Mediated PCR and Inverse PCR -- Quantitative PCR-Based Measurement of Nuclear and Mitochondrial DNA Damage and Repair in Mammalian Cells -- The Sister Chromatid Exchange (SCE) Assay -- The Gene Cluster Instability (GCI) Assay for Recombination -- Measuring Recombination Proficiency in Mouse Embryonic Stem Cells -- Microsatellite Instability: An Indirect Assay to Detect Defects in the Cellular Mismatch Repair Machinery -- Unscheduled DNA Synthesis: The Clinical and Functional Assay for Global Genomic Nucleotide Excision Repair -- An Immunoassay for Measuring Repair of UV Photoproducts -- Analysis of Double-Strand Break Repair by Non-Homologous DNA End Joining in Cell-Free Extracts from Mammalian Cells -- Bioenergetic Analysis of Intact Mammalian Cells Using the Seahorse XF42 Extracellular Flux Analyzer and a Luciferase ATP Assay -- Quantification of Selective Phosphatidylserine Oxidation During Apoptosis -- Quantitative Method of Measuring Phophatidylserine Externalization During Apoptosis Using Electron Paramagnetic Resonance (EPR) Spectroscopy and Annexin-Conjugated Iron -- Detection of Programmed Cell Death in Cells Exposed to Genotoxic Agents Using a Caspase Activation Assay.
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| 650 |
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0 |
|a Pharmacology.
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| 650 |
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0 |
|a Human genetics.
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| 650 |
1 |
4 |
|a Pharmacology/Toxicology.
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| 650 |
2 |
4 |
|a Human Genetics.
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| 700 |
1 |
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|a Keohavong, Phouthone.
|e editor.
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| 700 |
1 |
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|a Grant, Stephen G.
|e editor.
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| 710 |
2 |
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|a SpringerLink (Online service)
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| 773 |
0 |
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|t Springer eBooks
|