High Content Screening /

Detalles Bibliográficos
Autor Corporativo: SpringerLink (Online service)
Otros Autores: Taylor, D. Lansing. (Editor )
Formato: eBook
Lenguaje:English
Publicado: Totowa, NJ : Humana Press : Imprint: Humana, 2006.
Edición:1st ed. 2006.
Colección:Methods in Molecular Biology, 356
Materias:
Tabla de Contenidos:
  • to High Content Screening
  • Past, Present, and Future of High Content Screening and the Field of Cellomics
  • A Pharmaceutical Company User’s Perspective on the Potential of High Content Screening in Drug Discovery
  • Linking Microscopy and High Content Screening in Large-Scale Biomedical Research
  • Instrumentation, Biological Application Software, and Sample Preparation
  • Requirements, Features, and Performance of High Content Screening Platforms
  • Characteristics and Value of Directed Algorithms in High Content Screening
  • Characteristics and Value of Machine Learning for Imaging in High Content Screening
  • Tools for Quantitative and Validated Measurements of Cells
  • Automated Cell Plating and Sample Treatments for Fixed Cells in High Content Assays
  • Differentiating Primary Human Cells in Rapid-Throughput Discovery Applications
  • Use of the CellCard™ System for Analyzing Multiple Cell Types in Parallel
  • Reagents
  • Reagents to Measure and Manipulate Cell Functions
  • Fluorescent Proteins and Engineered Cell Lines
  • Optimizing the Integration of Immunoreagents and Fluorescent Probes for Multiplexed High Content Screening Assays
  • The HaloTag™
  • Protein Labeling With FlAsH and ReAsH
  • Exploiting Network Biology to Improve Drug Discovery
  • Physiological Indicators of Cell Function
  • The Use of siRNA to Validate Immunofluorescence Studies
  • Caged Substrates Applied to High Content Screening
  • Informatics and Bioinformatics
  • Overview of Informatics for High Content Screening
  • Large-Scale Data Management for High Content Screening
  • An Integrated Biomedical Knowledge Extraction and Analysis Platform
  • Visualization of High Content Screening Data
  • Pathway Mapping Tools for Analysis of High Content Data
  • Assays and Applications of High Content Screening
  • Systems Biology in Cancer Research
  • Target Validation in Drug Discovery
  • High Content Screening as a Screening Tool in Drug Discovery
  • Discovery of Protein Kinase Phosphatase Inhibitors
  • High Content Translocation Assays for Pathway Profiling
  • In Vitro Cytotoxicity Assessment
  • Neurite Outgrowth in Retinal Ganglion Cell Culture.