High Content Screening /
Autor Corporativo: | |
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Otros Autores: | |
Formato: | eBook |
Lenguaje: | English |
Publicado: |
Totowa, NJ :
Humana Press : Imprint: Humana,
2006.
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Edición: | 1st ed. 2006. |
Colección: | Methods in Molecular Biology,
356 |
Materias: |
Tabla de Contenidos:
- to High Content Screening
- Past, Present, and Future of High Content Screening and the Field of Cellomics
- A Pharmaceutical Company User’s Perspective on the Potential of High Content Screening in Drug Discovery
- Linking Microscopy and High Content Screening in Large-Scale Biomedical Research
- Instrumentation, Biological Application Software, and Sample Preparation
- Requirements, Features, and Performance of High Content Screening Platforms
- Characteristics and Value of Directed Algorithms in High Content Screening
- Characteristics and Value of Machine Learning for Imaging in High Content Screening
- Tools for Quantitative and Validated Measurements of Cells
- Automated Cell Plating and Sample Treatments for Fixed Cells in High Content Assays
- Differentiating Primary Human Cells in Rapid-Throughput Discovery Applications
- Use of the CellCard™ System for Analyzing Multiple Cell Types in Parallel
- Reagents
- Reagents to Measure and Manipulate Cell Functions
- Fluorescent Proteins and Engineered Cell Lines
- Optimizing the Integration of Immunoreagents and Fluorescent Probes for Multiplexed High Content Screening Assays
- The HaloTag™
- Protein Labeling With FlAsH and ReAsH
- Exploiting Network Biology to Improve Drug Discovery
- Physiological Indicators of Cell Function
- The Use of siRNA to Validate Immunofluorescence Studies
- Caged Substrates Applied to High Content Screening
- Informatics and Bioinformatics
- Overview of Informatics for High Content Screening
- Large-Scale Data Management for High Content Screening
- An Integrated Biomedical Knowledge Extraction and Analysis Platform
- Visualization of High Content Screening Data
- Pathway Mapping Tools for Analysis of High Content Data
- Assays and Applications of High Content Screening
- Systems Biology in Cancer Research
- Target Validation in Drug Discovery
- High Content Screening as a Screening Tool in Drug Discovery
- Discovery of Protein Kinase Phosphatase Inhibitors
- High Content Translocation Assays for Pathway Profiling
- In Vitro Cytotoxicity Assessment
- Neurite Outgrowth in Retinal Ganglion Cell Culture.