Protein Misfolding Diseases : Methods and Protocols /
| Autor Corporativo: | |
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| Otros Autores: | |
| Formato: | eBook |
| Lenguaje: | English |
| Publicado: |
New York, NY :
Springer New York : Imprint: Humana,
2019.
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| Edición: | 1st ed. 2019. |
| Colección: | Methods in Molecular Biology,
1873 |
| Materias: |
Tabla de Contenidos:
- Biophysical and Spectroscopic Methods for Monitoring Protein Misfolding and Amyloid Aggregation
- Ultrasensitive RT-QuIC Seed Amplification Assays for Disease-Associated Tau, α-Synuclein, and Prion Aggregates
- Vesicle-Based Assays to Study Membrane Interactions of Amyloid Peptides
- Differential Scanning Fluorimetry and Hydrogen Deuterium Exchange Mass Spectrometry to Monitor the Conformational Dynamics of NBD1 in Cystic Fibrosis
- A Multipronged Method for Unveiling Subtle Structural-Functional Defects of Mutant Chaperone Molecules Causing Human Chaperonopathies
- High-Throughput Microplate-Based Fluorescence Assays for Studying Stochastic Aggregation of Superoxide Dismutase-1
- Methods for Structural Analysis of Amyloid Fibrils in Misfolding Diseases
- Assays for Light Chain Amyloidosis Formation and Cytotoxicity
- Monitoring Aggregate Clearance and Formation in Cell-Based Assays
- Monitoring Proteome Stress in Live Cells Using HaloTag-Based Fluorogenic Sensor
- Quantification of Protein Aggregates Using Bimolecular Fluorescence Complementation
- Screening Protein Aggregation in Cells Using Fluorescent Labels Coupled to Flow Cytometry
- Induction of Cu/Zn Superoxide Dismutase (SOD1) Aggregation in Living Cells
- A Cell Model for HSP60 Deficiencies: Modeling Different Levels of Chaperonopathies Leading to Oxidative Stress and Mitochondrial Dysfunction
- Super-Resolution Fluorescence Imaging of Mutant Huntingtin Aggregation in Cells
- Thermal Shift and Stability Assays of Disease-Related Misfolded Proteins Using Differential Scanning Fluorimetry
- Methods to Screen Compounds against Mutant p53 Misfolding and Aggregation for Cancer Therapeutics
- Early Stage Discovery and Validation of Pharmacological Chaperones for the Correction of Protein Misfolding Diseases
- Constructing Kinetically Controlled Denaturation Isotherms of Folded Proteins Using Denaturant-Pulse Chaperonin Binding
- In Vitro Prion Amplification Methodology for Inhibitor Screening
- SolubiS: Optimizing Protein Solubility by Minimal Point Mutations.