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03911nam a22003495i 4500 |
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190606s2019 xxu| s |||| 0|eng d |
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|a 9781493994243
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| 024 |
7 |
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|a 10.1007/978-1-4939-9424-3
|2 doi
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| 040 |
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|a Sistema de Bibliotecas del Tecnológico de Costa Rica
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| 245 |
1 |
0 |
|a NADPH Oxidases :
|b Methods and Protocols /
|c edited by Ulla G. Knaus, Thomas L. Leto.
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| 250 |
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|a 1st ed. 2019.
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| 260 |
# |
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|a New York, NY :
|b Springer New York :
|b Imprint: Humana,
|c 2019.
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| 300 |
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|a XV, 718 p. 155 illus., 111 illus. in color. :
|b online resource.
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| 336 |
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|a text
|b txt
|2 rdacontent
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| 337 |
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|a computer
|b c
|2 rdamedia
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| 338 |
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|a online resource
|b cr
|2 rdacarrier
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| 490 |
1 |
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|a Methods in Molecular Biology,
|v 1982
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| 505 |
0 |
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|a Intersecting Stories of the Phagocyte NADPH Oxidase and Chronic Granulomatous Disease -- Mammalian NADPH Oxidases -- Enhanced Immunoaffinity Purification of Human Neutrophil Flavocytochrome B for Structure Determination by Electron Microscopy -- Purification and Characterization of DUOX Peroxidase Homology Domains (PHDs) -- A Close-Up View of the Impact of Arachidonic Acid on the Phagocyte NADPH Oxidase -- NOX5 Cell-Free Assay for the High-Throughput Screening of Small Molecules -- Spectroscopy of NOX Protein Family Members -- Soluble Regulatory Proteins for Activation of NOX Family NADPH Oxidases -- Insights into the NOX NADPH Oxidases Using Heterologous Whole Cell Assays -- The X-CGD PLB-985 Cell Model for NOX2 Structure-Function Analysis -- Functional Characterization of DUOX Enzymes in Reconstituted Cell Models -- Guidelines for the Detection of NADPH Oxidases by Immunoblot and RT-qPCR -- Methods for Detection of NOX-Derived Superoxide Radical Anion and Hydrogen Peroxide in Cells -- HPLC-Based Monitoring of Oxidation of Hydroethidine for Detection of NADPH Oxidase-Derived Superoxide Radical Anion -- Visualization of Intracellular Hydrogen Peroxide with the Genetically-Encoded Fluorescent Probe HyPer in NIH-3T3 Cells -- Imaging Intracellular H2O2 with the Genetically-Encoded PerFRET and OxyFRET Probes -- Quantitative Imaging of Endogenous and Exogenous H2O2 Gradients in Live Zebrafish Larvae -- Kinetic Analysis of Phagosomal ROS Generation -- Imaging Intestinal ROS in Homeostatic Conditions Using L-012 -- Hydro-Cy3-Mediated Detection of Reactive Oxygen Species In Vitro and In Vivo -- Phosphorylation of Gp91phox/NOX2 in Human Neutrophils -- The Molecular Regulation and Functional Roles of NOX5 -- Using Synthetic Peptides for Exploring Protein-Protein Interactions in the Assembly of the NADPH Oxidase Complex -- Rational Design and Delivery of NOX-Inhibitory Peptides -- High-Throughput Screening of NOX Inhibitors -- Protein-Protein Interaction Assay to Analyze NOX4/p22phox Heterodimerization -- Isolation of Redox Active Endosomes (Redoxosomes) and Assessment of NOX Activity -- Model Systems to Investigate NOX-Dependent Cell Migration and Invasiveness -- NADPH Oxidases and Aging Models of Lung Fibrosis -- Proteomic Methods to Evaluate NOX-Mediated Redox Signaling -- Neutrophil Extracellular Traps -- Chronic Granulomatous Disease -- Diagnostic Testing for Chronic Granulomatous Disease -- Gastrointestinal Complications in Chronic Granulomatous Disease -- Ex Vivo Models of Chronic Granulomatous Disease -- Gene Editing in Chronic Granulomatous Disease -- DUOX Defects and Their Roles in Congenital Hypothyroidism -- NAPDH Oxidases in Inflammatory Bowel Disease.
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| 650 |
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0 |
|a Enzymology.
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| 650 |
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|a Human physiology.
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| 650 |
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0 |
|a Human genetics.
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| 650 |
1 |
4 |
|a Enzymology.
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| 650 |
2 |
4 |
|a Human Physiology.
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| 650 |
2 |
4 |
|a Human Genetics.
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| 700 |
1 |
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|a Knaus, Ulla G.
|e editor.
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| 700 |
1 |
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|a Leto, Thomas L.
|e editor.
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| 710 |
2 |
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|a SpringerLink (Online service)
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| 773 |
0 |
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|t Springer eBooks
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| 900 |
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|a Libro descargado a ALEPH en bloque (proveniente de proveedor)
|