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03521nam a22003015i 4500 |
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110912s2011 xxu| s |||| 0|eng d |
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|a 9781617793288
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024 |
7 |
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|a 10.1007/978-1-61779-328-8
|2 doi
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040 |
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|a Sistema de Bibliotecas del Tecnológico de Costa Rica
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245 |
1 |
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|a Neurodegeneration :
|b Methods and Protocols /
|c edited by Giovanni Manfredi, Hibiki Kawamata.
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250 |
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|a 1st ed. 2011.
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260 |
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|a Totowa, NJ :
|b Humana Press :
|b Imprint: Humana,
|c 2011.
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300 |
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|a XV, 512 p. 100 illus., 9 illus. in color. :
|b online resource.
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336 |
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|a text
|b txt
|2 rdacontent
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|a computer
|b c
|2 rdamedia
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338 |
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|a online resource
|b cr
|2 rdacarrier
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490 |
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|a Methods in Molecular Biology,
|v 793
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505 |
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|a Introduction to Neurodegenerative Diseases and Related Techniques -- In vivo and In vitro Determination of Cell Death Markers in Neurons -- Degenerating Processes Identified by Electron Microscopic Immunocytochemical Methods -- Isolation and Culture of Neurons and Astrocytes from the Mouse Brain Cortex -- Isolation and Culture of Postnatal Spinal Motoneurons -- Converting Human Pluripotent Stem Cells to Neural Tissue and Neurons to Model Neurodegeneration -- Neural Differentiation of Induced Pluripotent Stem Cells -- Developing Yeast Models of Human Neurodegenerative Disorders -- Modeling Dopamine Neuron Degeneration in C. elegans -- Role of the Proteasome in Fly Models of Neurodegeneration -- Modeling Neurodegenerative Diseases in Zebrafish Embryos -- Practical Considerations of Genetic Rodent Models for Neurodegenerative Diseases -- Modeling Focal Cerebral Ischemia In vivo -- Pharmacological Models of Parkison's Disease in Rodents -- Behavioral Phenotyping of Mouse Models of Neurodegeneration -- Characterization of Amyloid Deposits in Neurodegenerative Diseases -- Detection of Protein Aggregates in Neurodegenerative Diseases -- Assessment of Proteasome Impairment and Accumulation/Aggregation of Ubiquitinated Proteins in Neuronal Cultures -- Measurements of Threshold of Mitochondrial Transition Pore Opening in Intact and Permeabilized Cells by Flash Photolysis of Caged Calcium -- Isolation and Functional Assessment of Mitochondria from Small Amounts of Mouse Brain Tissue -- Monitoring Mitophagy in Neuronal Cell Cultures -- Analysis of Vesicular Trafficking in Primary Neurons by Live Imaging -- Surface Trafficking of Sodium Channels in Cells and in Hippocampal Slices -- Imaging Presynaptic Exocytosis in Corticostriatal Slices -- Microscopic Imaging of Intracellular Calcium in Live Cells using Lifetime based Ratiometric Measurements of Oregon Green BAPTA-1 -- Electrophysiological Characterization of Neuromuscular Synaptic Dysfunction in Mice -- Determination of Neurotransmitter Levels in Models of Parkinson’s Disease by HPLC-ECD -- Designing, Performing, and Interpreting a Microarray-based Gene Expression Study -- Adeno-associated Viral Gene Transfer for Neurodegenerative Diseases -- Specific Gene Silencing using RNAi in Cell Culture -- Stem Cell Transplantation for Spinal Cord Neurodegeneration -- Evaluation of Histone Deacetylase Inhibitors as Therapeutics for Neurodegenerative Diseases.
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650 |
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|a Neurosciences.
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650 |
1 |
4 |
|a Neurosciences.
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700 |
1 |
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|a Manfredi, Giovanni.
|e editor.
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700 |
1 |
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|a Kawamata, Hibiki.
|e editor.
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710 |
2 |
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|a SpringerLink (Online service)
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773 |
0 |
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|t Springer eBooks
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900 |
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|a Libro descargado a ALEPH en bloque (proveniente de proveedor)
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