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141015s2015 xxu| s |||| 0|eng d |
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|a 9781493917891
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| 024 |
7 |
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|a 10.1007/978-1-4939-1789-1
|2 doi
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| 040 |
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|a Sistema de Bibliotecas del Tecnológico de Costa Rica
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| 245 |
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|a Receptor Tyrosine Kinases :
|b Methods and Protocols /
|c edited by Serena Germano.
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| 250 |
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|a 1st ed. 2015.
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| 260 |
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|a New York, NY :
|b Springer New York :
|b Imprint: Humana,
|c 2015.
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| 300 |
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|a XI, 181 p. 38 illus., 31 illus. in color. :
|b online resource.
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| 336 |
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|a text
|b txt
|2 rdacontent
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| 337 |
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|a computer
|b c
|2 rdamedia
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| 338 |
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|a online resource
|b cr
|2 rdacarrier
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| 490 |
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|a Methods in Molecular Biology,
|v 1233
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| 505 |
0 |
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|a Analysis of Receptor Tyrosine Kinase (RTK) Phosphorylation by Immunoblotting -- Analysis of Changes in Phosphorylation of Receptor Tyrosine Kinases: Antibody Arrays -- Analysis of Epidermal Growth Factor Receptor Dimerization by BS3 Crosslinking -- Single-Molecule Optical Methods Analyzing Receptor Tyrosine Kinase Activation in Living Cells -- Evaluation of the Dimerization Profiles of HER Tyrosine Kinases by Time-Resolved Förster Resonance Energy Transfer (TR-FRET) -- Applying the Proximity Ligation Assay (PLA) to Mouse Preimplantation Embryos for Identifying Protein-Protein Interactions In Situ -- Analysis of Receptor Tyrosine Kinase Gene Amplification on the Example of FGFR1 -- Quantification of the Effects of Mutations on Receptor Tyrosine Kinase (RTK) Activation in Mammalian Cells -- Cell Surface Biotinylation of Receptor Tyrosine Kinases to Investigate Intracellular Trafficking -- Studying N-Linked Glycosylation of Receptor Tyrosine Kinases -- Identification of Receptor Protein Tyrosine Phosphatases (RPTPs) as Regulators of Receptor Tyrosine Kinases (RTKs) Using an RPTP siRNA-RTK Substrate Screen -- Downregulation of Receptor Tyrosine Kinases Through Ubiquitination: Analysis by Immunodetection -- Regulation of Receptor Tyrosine Kinases by miRNA: Overexpression of miRNA Using Lentiviral Inducible Expression Vectors -- Human Tumor Xenografts in Mouse as a Model for Evaluating Therapeutic Efficacy of Monoclonal Antibodies or Antibody-Drug Conjugate Targeting Receptor Tyrosine Kinases -- Receptor Tyrosine Kinase Targeting in Multicellular Spheroids -- Receptor Tyrosine Kinases and Drug Resistance: Development and Characterization of In Vitro Models of Resistance to RTK Inhibitors.
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| 650 |
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|a Proteins .
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| 650 |
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|a Cell membranes .
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| 650 |
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4 |
|a Protein Science.
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| 650 |
2 |
4 |
|a Membrane Biology.
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| 700 |
1 |
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|a Germano, Serena.
|e editor.
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| 710 |
2 |
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|a SpringerLink (Online service)
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| 773 |
0 |
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|t Springer eBooks
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