Receptor Tyrosine Kinases : Methods and Protocols /

Detalles Bibliográficos
Autor Corporativo: SpringerLink (Online service)
Otros Autores: Germano, Serena. (Editor )
Formato: eBook
Lenguaje:English
Publicado: New York, NY : Springer New York : Imprint: Humana, 2015.
Edición:1st ed. 2015.
Colección:Methods in Molecular Biology, 1233
Materias:
Tabla de Contenidos:
  • Analysis of Receptor Tyrosine Kinase (RTK) Phosphorylation by Immunoblotting
  • Analysis of Changes in Phosphorylation of Receptor Tyrosine Kinases: Antibody Arrays
  • Analysis of Epidermal Growth Factor Receptor Dimerization by BS3 Crosslinking
  • Single-Molecule Optical Methods Analyzing Receptor Tyrosine Kinase Activation in Living Cells
  • Evaluation of the Dimerization Profiles of HER Tyrosine Kinases by Time-Resolved Förster Resonance Energy Transfer (TR-FRET)
  • Applying the Proximity Ligation Assay (PLA) to Mouse Preimplantation Embryos for Identifying Protein-Protein Interactions In Situ
  • Analysis of Receptor Tyrosine Kinase Gene Amplification on the Example of FGFR1
  • Quantification of the Effects of Mutations on Receptor Tyrosine Kinase (RTK) Activation in Mammalian Cells
  • Cell Surface Biotinylation of Receptor Tyrosine Kinases to Investigate Intracellular Trafficking
  • Studying N-Linked Glycosylation of Receptor Tyrosine Kinases
  • Identification of Receptor Protein Tyrosine Phosphatases (RPTPs) as Regulators of Receptor Tyrosine Kinases (RTKs) Using an RPTP siRNA-RTK Substrate Screen
  • Downregulation of Receptor Tyrosine Kinases Through Ubiquitination: Analysis by Immunodetection
  • Regulation of Receptor Tyrosine Kinases by miRNA: Overexpression of miRNA Using Lentiviral Inducible Expression Vectors
  • Human Tumor Xenografts in Mouse as a Model for Evaluating Therapeutic Efficacy of Monoclonal Antibodies or Antibody-Drug Conjugate Targeting Receptor Tyrosine Kinases
  • Receptor Tyrosine Kinase Targeting in Multicellular Spheroids
  • Receptor Tyrosine Kinases and Drug Resistance: Development and Characterization of In Vitro Models of Resistance to RTK Inhibitors.