Progranulin : Methods and Protocols /
| Autor Corporativo: | |
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| Otros Autores: | , , |
| Formato: | eBook |
| Lenguaje: | English |
| Publicado: |
New York, NY :
Springer New York : Imprint: Humana,
2018.
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| Edición: | 1st ed. 2018. |
| Colección: | Methods in Molecular Biology,
1806 |
| Materias: |
Tabla de Contenidos:
- A Brief Overview of Progranulin in Health and Disease
- Chromatographic Methods for the Purification of Granulin Peptides
- Methods for Expression and Purification of Biologically Active Recombinant Progranulin
- Large-Scale Generation of Recombinant Granulin Peptides in E. coli
- Nuclear Magnetic Resonance Spectroscopy in Analysis of Granulin Three-Dimensional Structure and Cysteine Bridging
- Data Mining: Applying the AD&FTD Mutation Database to Progranulin
- Measurement of Circulating Progranulin (PGRN/GP88/GEP) by Enzyme-Linked Immunosorbent Assay and Application in Human Diseases
- Immunohistochemical Detection of Progranulin (PGRN/GP88/GEP) in Tumor Tissues as a Cancer Prognostic Biomarker
- Analysis of Progranulin-Mediated Akt and MAPK Activation
- Mouse Monoclonal Antibodies Against Progranulin (PGRN/GEP) as Therapeutics in Preclinical Cancer Models
- Methods to Analyze the Role of Progranulin (PGRN/GEP) on Cancer Stem Cell Features
- Methods to Study the Role of Progranulin in the Tumor Microenvironment
- Methods to Investigate the Molecular Basis of Progranulin Action on Neurons In Vivo using Caenorhabditis elegans
- The Use of Caenorhabditis elegans to Study Progranulin in the Regulation of Programmed Cell Death and Stress Response
- Application of Zebrafish and Knockdown Technology to Define Progranulin Neuronal Function
- Methods to Investigate the Molecular Basis of Progranulin Actions on Brain and Behavior In Vivo Using Knockout Mice
- Methods to Investigate the Protection Againts Neurodegenerative Disorders Provided by Progranulin Gene Transfer in the Brain
- The Interaction between Progranulin with Sortilin and the Lysosome
- Methods to Study the Role of Progranulin in Preimplanatation Mouse Embryo Development
- Establishment of a Modified Collagen-Induced Arthritis Mouse Model to Investigate the Anti-Inflammatory Activity of Progranulin in Inflammatory Arthritis
- Methods for Studying the Function of Progranulin in Atherosclerosis using Both Knockout Mice Models and In Vitro Studies
- Methods to Investigate the Roles of Prgranulin in Angiogenesis Using In Vitro Strategies and Transgenic Mouse Models.