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02439nam a22003255i 4500 |
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120919s2012 xxu| s |||| 0|eng d |
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|a 9781627030779
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024 |
7 |
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|a 10.1007/978-1-62703-077-9
|2 doi
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040 |
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|a Sistema de Bibliotecas del Tecnológico de Costa Rica
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245 |
1 |
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|a TRP Channels in Drug Discovery :
|b Volume I /
|c edited by Arpad Szallasi, Tamás Bíró.
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250 |
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|a 1st ed. 2012.
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260 |
# |
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|a Totowa, NJ :
|b Humana Press :
|b Imprint: Humana,
|c 2012.
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300 |
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|a XI, 446 p. 39 illus., 13 illus. in color. :
|b online resource.
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336 |
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|a text
|b txt
|2 rdacontent
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|a computer
|b c
|2 rdamedia
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338 |
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|a online resource
|b cr
|2 rdacarrier
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490 |
1 |
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|a Methods in Pharmacology and Toxicology,
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505 |
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|a Introduction to TRPs: A Quest for Novel Drug Targets -- TRP-Mediated Cytoskeletal Reorganization: Implications for Disease and Drug Development -- TRPA1 in Drug Discovery -- Canonical Transient Receptor Potential Channel (TRPC) Expression, Regulation, and Function in Vascular and Airway Diseases -- TRPM2 Function and Potential as a Drug Target -- The Ca2+-Activated Monovalent Cation Selective Channels TRPM4 and TRPM5 -- The Emerging Role of TRPM7 in the Regulation of Magnesium Homeostasis -- TRPM8 Channels as Potential Therapeutic Targets for Pain, Analgesia, and Thermoregulation -- TRPML Channels in Function, Disease, and Prospective Therapies -- The TRPP Signalling Module: TRPP2/Polycystin 1 and TRPP2/PKD1L1 -- TRPV1 as a Polymodal Sensor: Potential to Discover TRPV1 Antagonists Selective for Specific Activating Modalities -- Nociceptive and Non-Nociceptive Roles of TRPV3 and Its “Druggability” -- TRPV4 and Drug Discovery -- TRP Expression and Function in the Lung Airways -- Hypoxia-Dependent TRP Channel Function in Pulmonary Arterial Smooth Muscle Cells -- Endotoxin-Induced Airway Inflammation and Asthma Models -- Enhanced Cough, Animal Models -- Capsaicin Inhalation Test in Man -- TRP Channels in the Genitourinary (GU) Tract -- Animal Models of Cystitis -- Overactive Bladder Models.
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650 |
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|a Pharmacology.
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650 |
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|a Proteomics.
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650 |
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4 |
|a Pharmacology/Toxicology.
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650 |
2 |
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|a Proteomics.
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700 |
1 |
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|a Szallasi, Arpad.
|e editor.
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700 |
1 |
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|a Bíró, Tamás.
|e editor.
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710 |
2 |
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|a SpringerLink (Online service)
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773 |
0 |
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|t Springer eBooks
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856 |
4 |
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|u https://doi.org/10.1007/978-1-62703-077-9
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