TRP Channels in Drug Discovery : Volume I /

Detalles Bibliográficos
Autor Corporativo: SpringerLink (Online service)
Otros Autores: Szallasi, Arpad. (Editor ), Bíró, Tamás. (Editor )
Formato: eBook
Lenguaje:English
Publicado: Totowa, NJ : Humana Press : Imprint: Humana, 2012.
Edición:1st ed. 2012.
Colección:Methods in Pharmacology and Toxicology,
Materias:
Acceso en línea:https://doi.org/10.1007/978-1-62703-077-9
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245 1 0 |a TRP Channels in Drug Discovery :  |b Volume I /  |c edited by Arpad Szallasi, Tamás Bíró. 
250 |a 1st ed. 2012. 
260 # # |a Totowa, NJ :  |b Humana Press :  |b Imprint: Humana,  |c 2012. 
300 |a XI, 446 p. 39 illus., 13 illus. in color. :  |b online resource. 
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337 |a computer  |b c  |2 rdamedia 
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490 1 |a Methods in Pharmacology and Toxicology, 
505 0 |a Introduction to TRPs: A Quest for Novel Drug Targets -- TRP-Mediated Cytoskeletal Reorganization: Implications for Disease and Drug Development -- TRPA1 in Drug Discovery -- Canonical Transient Receptor Potential Channel (TRPC) Expression, Regulation, and Function in Vascular and Airway Diseases -- TRPM2 Function and Potential as a Drug Target -- The Ca2+-Activated Monovalent Cation Selective Channels TRPM4 and TRPM5 -- The Emerging Role of TRPM7 in the Regulation of Magnesium Homeostasis -- TRPM8 Channels as Potential Therapeutic Targets for Pain, Analgesia, and Thermoregulation -- TRPML Channels in Function, Disease, and Prospective Therapies -- The TRPP Signalling Module: TRPP2/Polycystin 1 and TRPP2/PKD1L1 -- TRPV1 as a Polymodal Sensor: Potential to Discover TRPV1 Antagonists Selective for Specific Activating Modalities -- Nociceptive and Non-Nociceptive Roles of TRPV3 and Its “Druggability” -- TRPV4 and Drug Discovery -- TRP Expression and Function in the Lung Airways -- Hypoxia-Dependent TRP Channel Function in Pulmonary Arterial Smooth Muscle Cells -- Endotoxin-Induced Airway Inflammation and Asthma Models -- Enhanced Cough, Animal Models -- Capsaicin Inhalation Test in Man -- TRP Channels in the Genitourinary (GU) Tract -- Animal Models of Cystitis -- Overactive Bladder Models. 
650 0 |a Pharmacology. 
650 0 |a Proteomics. 
650 1 4 |a Pharmacology/Toxicology. 
650 2 4 |a Proteomics. 
700 1 |a Szallasi, Arpad.  |e editor. 
700 1 |a Bíró, Tamás.  |e editor. 
710 2 |a SpringerLink (Online service) 
773 0 |t Springer eBooks 
856 4 0 |u https://doi.org/10.1007/978-1-62703-077-9