TRP Channels in Drug Discovery : Volume I /
| Autor Corporativo: | |
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| Otros Autores: | , |
| Formato: | eBook |
| Lenguaje: | English |
| Publicado: |
Totowa, NJ :
Humana Press : Imprint: Humana,
2012.
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| Edición: | 1st ed. 2012. |
| Colección: | Methods in Pharmacology and Toxicology,
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| Materias: | |
| Acceso en línea: | https://doi.org/10.1007/978-1-62703-077-9 |
Tabla de Contenidos:
- Introduction to TRPs: A Quest for Novel Drug Targets
- TRP-Mediated Cytoskeletal Reorganization: Implications for Disease and Drug Development
- TRPA1 in Drug Discovery
- Canonical Transient Receptor Potential Channel (TRPC) Expression, Regulation, and Function in Vascular and Airway Diseases
- TRPM2 Function and Potential as a Drug Target
- The Ca2+-Activated Monovalent Cation Selective Channels TRPM4 and TRPM5
- The Emerging Role of TRPM7 in the Regulation of Magnesium Homeostasis
- TRPM8 Channels as Potential Therapeutic Targets for Pain, Analgesia, and Thermoregulation
- TRPML Channels in Function, Disease, and Prospective Therapies
- The TRPP Signalling Module: TRPP2/Polycystin 1 and TRPP2/PKD1L1
- TRPV1 as a Polymodal Sensor: Potential to Discover TRPV1 Antagonists Selective for Specific Activating Modalities
- Nociceptive and Non-Nociceptive Roles of TRPV3 and Its “Druggability”
- TRPV4 and Drug Discovery
- TRP Expression and Function in the Lung Airways
- Hypoxia-Dependent TRP Channel Function in Pulmonary Arterial Smooth Muscle Cells
- Endotoxin-Induced Airway Inflammation and Asthma Models
- Enhanced Cough, Animal Models
- Capsaicin Inhalation Test in Man
- TRP Channels in the Genitourinary (GU) Tract
- Animal Models of Cystitis
- Overactive Bladder Models.