Systems Biology of Alzheimer's Disease /

Detalles Bibliográficos
Autor Corporativo: SpringerLink (Online service)
Otros Autores: Castrillo, Juan I. (Editor ), Oliver, Stephen G. (Editor )
Formato: eBook
Lenguaje:English
Publicado: New York, NY : Springer New York : Imprint: Humana, 2016.
Edición:1st ed. 2016.
Colección:Methods in Molecular Biology, 1303
Materias:
Tabla de Contenidos:
  • Alzheimer’s as a Systems-Level Disease Involving the Interplay of Multiple Cellular Networks
  • Application of Systems Theory in Longitudinal Studies on the Origin and Progression of Alzheimer’s Disease
  • The APP Proteolytic System and Its Interactions with Dynamic Networks in Alzheimer’s Disease
  • Effects of Mild and Severe Oxidative Stress on BACE1 Expression and APP Amyloidogenic Processing
  • Advanced Assay Monitoring APP-Carboxyl-Terminal Fragments as Markers of APP Processing in Alzheimer Disease Mouse Models
  • Advanced Optical Super-Resolution Method and Techniques for the Study of β-Amyloid Aggregation In Vitro and In Vivo
  • Protocols for Monitoring the Development of Tau Pathology in Alzheimer’s Disease
  • LC3-II Tagging and Western Blotting for Monitoring Autophagic Activity in Mammalian Cells
  • Advanced Mitochondrial Respiration Assay for Evaluation of Mitochondrial Dysfunction in Alzheimer’s Disease
  • Analysis of Microglial Proliferation in Alzheimer’s Disease
  • Yeast as a Model for Alzheimer’s Disease: Latest Studies and Advanced Strategies
  • Yeast as a Model for Studies on Aβ Aggregation Toxicity in Alzheimer’s Disease, Autophagic Responses, and Drug Screening
  • Drosophila melanogaster as a Model for Studies on the Early Stages of Alzheimer’s Disease
  • Chronic Mild Stress Assay Leading to Early Onset and Propagation of Alzheimer’s Disease Phenotype in Mouse Models
  • Gene Expression Studies on Human Trisomy 21 iPSCs and Neurons: Towards Mechanisms Underlyi ng Down’s Syndrome and Early Alzheimer’s Disease-Like Pathologies
  • Cortical Differentiation of Human Pluripotent Cells for In Vitro Modeling of Alzheimer’s Disease
  • Next Generation Sequencing in Alzheimer’s Disease
  • Pooled-DNA Sequencing for Elucidating New Genomic Risk Factors, Rare Variants Underlying Alzheimer’s Disease
  • New Genome-Wide Methods for Elucidation of Candidate Copy Number Variations (CNVs) Contributing to Alzheimer’s Disease Heritability
  • RNA-Sequencing to Elucidate Early Patterns of Dysregulation Underlying the Onset of Alzheimer’s Disease
  • Systems Biology Approaches to the Study of Biological Networks Underlying Alzheimer’s Disease: Role of miRNAs
  • The Emerging Role of Metalloproteomics in Alzheimer’s Disease Research
  • Redox Proteomics in Human Biofluids: Sample Preparation, Separation and Immunochemical Tagging for Analysis of Protein Oxidation
  • Advanced Shotgun Lipidomics for Characterization of Altered Lipid Patterns in Neurodegenerative Diseases and Brain Injury
  • AlzPathway, an Updated Map of Curated Signaling Pathways: Towards Deciphering Alzheimer’s Disease Pathogenesis
  • A Computational Network Biology Approach to Uncover Novel Genes Related to Alzheimer’s Disease
  • Network Approaches to the Understanding of Alzheimer’s Disease: From Model Organisms to Humans
  • Characterization of Genetic Networks Associated with Alzheimer's Disease
  • Network-Based Analysis for Uncovering Mechanisms Underlying Alzheimer’s Disease
  • The SDREM Method for Reconstructing Signaling and Regulatory Response Networks: Applications for Studying Disease Progression
  • Advanced Neuroimaging Methods Towards Characterization of Early Stages of Alzheimer’s Disease
  • Plasma Proteomics Biomarkers in Alzheimer's Disease: Latest Advances and Challenges
  • A Practical Guide For Exploring Opportunities of Repurposing Drugs for CNS Diseases in Systems Biology.