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03394nam a22003255i 4500 |
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20210614145930.0 |
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120627s2012 xxu| s |||| 0|eng d |
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|a 9781617799211
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024 |
7 |
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|a 10.1007/978-1-61779-921-1
|2 doi
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040 |
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|a Sistema de Bibliotecas del Tecnológico de Costa Rica
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245 |
1 |
0 |
|a Therapeutic Proteins :
|b Methods and Protocols /
|c edited by Vladimir Voynov, Justin A. Caravella.
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250 |
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|a 2nd ed. 2012.
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260 |
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|a Totowa, NJ :
|b Humana Press :
|b Imprint: Humana,
|c 2012.
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300 |
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|a XI, 502 p. 107 illus., 50 illus. in color. :
|b online resource.
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336 |
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|a text
|b txt
|2 rdacontent
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|a computer
|b c
|2 rdamedia
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338 |
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|a online resource
|b cr
|2 rdacarrier
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490 |
1 |
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|a Methods in Molecular Biology,
|v 899
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505 |
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|a Therapeutic Proteins -- Synthetic Antibody Libraries -- The Construction of ‘Phylomer’ Peptide Libraries as a Rich Source of Potent Inhibitors of Protein/Protein Interactions -- Ribosome Display and Screening for Protein Therapeutics -- Yeast Display of Engineered Antibody Domains -- Design, Expression, Purification, and Characterization of Engineered Antibody CH2 and VH Domains -- Engineering of Affibody Molecules for Therapy and Diagnostics -- Protein Design for Diversity of Sequences and Conformations Using Dead-End Elimination -- Design and Generation of DVD-IgTM Molecules for Dual-Specific Targeting -- Engineering and Expression of Bibody and Tribody Constructs in Mammalian Cells and in the Yeast Pichia pastoris -- Use of E. coli for the Production of a Single Protein -- Folding Engineering Strategies for Efficient Membrane Protein Production in E. coli -- Transient Expression Technologies: Past, Present, and Future -- Stable Transfection Pools for Large Quantity of Protein Production -- Mammalian Stable Expression of Biotherapeutics -- Transgenic Expression of Therapeutic Proteins in Arabidopsis thaliana Seed -- Methods for Chromatographic Removal of Endotoxin -- Effectiveness of Various Processing Steps for Viral Clearance of Therapeutic Proteins: Database Analyses of Commonly-Used Steps -- High-Throughput Quantitative N-Glycan Analysis of Glycoproteins -- High-Throughput Multimodal Strong Anion Exchange Purification and N-Glycan Characterization of Endogenous Glycoprotein Expressed in Glycoengineered Pichia pastoris -- Databases and Tools in Glycobiology -- Characterization of PEGylated Biopharmaceutical Products by LC/MS and LC/MS/MS -- Identification of Asp Isomerization in Proteins by 18O Labeling and Tandem Mass Spectrometry -- Monitoring of Subvisible Particles in Therapeutic Proteins -- Size-Exclusion Chromatography with Multi-Angle Light Scattering (SEC-MALS) for Elucidating Protein Aggregation Mechanisms -- Computational Methods to Predict Therapeutic Protein Aggregation -- Coarse-Grained Simulations of Protein Aggregation -- Chitosan-Based Nanoparticles as Delivery Systems of Therapeutic Proteins -- Challenges in the Development and Manufacturing of Antibody-Drug Conjugates.
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650 |
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|a Pharmacology.
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650 |
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|a Proteomics.
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650 |
1 |
4 |
|a Pharmacology/Toxicology.
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650 |
2 |
4 |
|a Proteomics.
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700 |
1 |
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|a Voynov, Vladimir.
|e editor.
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700 |
1 |
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|a Caravella, Justin A.
|e editor.
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710 |
2 |
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|a SpringerLink (Online service)
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773 |
0 |
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|t Springer eBooks
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900 |
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|a Libro descargado a ALEPH en bloque (proveniente de proveedor)
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