Therapeutic Proteins : Methods and Protocols /

Detalles Bibliográficos
Autor Corporativo: SpringerLink (Online service)
Otros Autores: Voynov, Vladimir. (Editor ), Caravella, Justin A. (Editor )
Formato: eBook
Lenguaje:English
Publicado: Totowa, NJ : Humana Press : Imprint: Humana, 2012.
Edición:2nd ed. 2012.
Colección:Methods in Molecular Biology, 899
Materias:
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020 |a 9781617799211 
024 7 |a 10.1007/978-1-61779-921-1  |2 doi 
040 |a Sistema de Bibliotecas del Tecnológico de Costa Rica 
245 1 0 |a Therapeutic Proteins :  |b Methods and Protocols /  |c edited by Vladimir Voynov, Justin A. Caravella. 
250 |a 2nd ed. 2012. 
260 # # |a Totowa, NJ :  |b Humana Press :  |b Imprint: Humana,  |c 2012. 
300 |a XI, 502 p. 107 illus., 50 illus. in color. :  |b online resource. 
336 |a text  |b txt  |2 rdacontent 
337 |a computer  |b c  |2 rdamedia 
338 |a online resource  |b cr  |2 rdacarrier 
490 1 |a Methods in Molecular Biology,  |v 899 
505 0 |a Therapeutic Proteins -- Synthetic Antibody Libraries -- The Construction of ‘Phylomer’ Peptide Libraries as a Rich Source of Potent Inhibitors of Protein/Protein Interactions -- Ribosome Display and Screening for Protein Therapeutics -- Yeast Display of Engineered Antibody Domains -- Design, Expression, Purification, and Characterization of Engineered Antibody CH2 and VH Domains -- Engineering of Affibody Molecules for Therapy and Diagnostics -- Protein Design for Diversity of Sequences and Conformations Using Dead-End Elimination -- Design and Generation of DVD-IgTM Molecules for Dual-Specific Targeting -- Engineering and Expression of Bibody and Tribody Constructs in Mammalian Cells and in the Yeast Pichia pastoris -- Use of E. coli for the Production of a Single Protein -- Folding Engineering Strategies for Efficient Membrane Protein Production in E. coli -- Transient Expression Technologies: Past, Present, and Future -- Stable Transfection Pools for Large Quantity of Protein Production -- Mammalian Stable Expression of Biotherapeutics -- Transgenic Expression of Therapeutic Proteins in Arabidopsis thaliana Seed -- Methods for Chromatographic Removal of Endotoxin -- Effectiveness of Various Processing Steps for Viral Clearance of Therapeutic Proteins: Database Analyses of Commonly-Used Steps -- High-Throughput Quantitative N-Glycan Analysis of Glycoproteins -- High-Throughput Multimodal Strong Anion Exchange Purification and N-Glycan Characterization of Endogenous Glycoprotein Expressed in Glycoengineered Pichia pastoris -- Databases and Tools in Glycobiology -- Characterization of PEGylated Biopharmaceutical Products by LC/MS and LC/MS/MS -- Identification of Asp Isomerization in Proteins by 18O Labeling and Tandem Mass Spectrometry -- Monitoring of Subvisible Particles in Therapeutic Proteins -- Size-Exclusion Chromatography with Multi-Angle Light Scattering (SEC-MALS) for Elucidating Protein Aggregation Mechanisms -- Computational Methods to Predict Therapeutic Protein Aggregation -- Coarse-Grained Simulations of Protein Aggregation -- Chitosan-Based Nanoparticles as Delivery Systems of Therapeutic Proteins -- Challenges in the Development and Manufacturing of Antibody-Drug Conjugates. 
650 0 |a Pharmacology. 
650 0 |a Proteomics. 
650 1 4 |a Pharmacology/Toxicology. 
650 2 4 |a Proteomics. 
700 1 |a Voynov, Vladimir.  |e editor. 
700 1 |a Caravella, Justin A.  |e editor. 
710 2 |a SpringerLink (Online service) 
773 0 |t Springer eBooks 
900 |a Libro descargado a ALEPH en bloque (proveniente de proveedor)