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02833nam a22003255i 4500 |
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20211008083052.0 |
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cr nn 008mamaa |
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130531s2013 xxu| s |||| 0|eng d |
| 020 |
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|a 9781627034388
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| 024 |
7 |
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|a 10.1007/978-1-62703-438-8
|2 doi
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| 040 |
|
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|a Sistema de Bibliotecas del Tecnológico de Costa Rica
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| 245 |
1 |
0 |
|a Tandem Repeats in Genes, Proteins, and Disease :
|b Methods and Protocols /
|c edited by Danny M. Hatters, Anthony J. Hannan.
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| 250 |
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|a 1st ed. 2013.
|
| 260 |
# |
# |
|a Totowa, NJ :
|b Humana Press :
|b Imprint: Humana,
|c 2013.
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| 300 |
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|a XI, 258 p. 55 illus., 23 illus. in color. :
|b online resource.
|
| 336 |
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|a text
|b txt
|2 rdacontent
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| 337 |
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|a computer
|b c
|2 rdamedia
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| 338 |
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|a online resource
|b cr
|2 rdacarrier
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| 490 |
1 |
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|a Methods in Molecular Biology,
|v 1017
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| 505 |
0 |
|
|a Longitudinal Imaging and Analysis of Neurons Expressing Polyglutamine-Expanded Proteins -- Atomic Force Microscopy Assays for Evaluating Polyglutamine Aggregation in Solution and on Surfaces -- Morphometric Analysis of Huntington’s Disease Neurodegeneration in Drosophila -- Size Analysis of Polyglutamine Protein Aggregates using Fluorescence Detection in an Analytical Ultracentrifuge -- A Method for the Incremental Expansion of Polyglutamine Repeats in Recombinant Proteins -- Pulse Shape Analysis (PulSA) to Track Protein Translocalization in Cells by Flow Cytometry: Applications for Polyglutamine Aggregation -- Characterizing Social Behavior in Genetically Targeted Mouse Models of Brain Disorders -- PCR Amplification and Sequence Analysis of GC-rich Sequences: Aristaless-Related Homeobox Example -- Challenges of “sticky” Co-Immunoprecipitation; Polyalanine Tract Protein-Protein Interactions -- Molecular Pathology of Polyalanine Expansion Disorders-new Perspectives from Mouse Models -- Yeast as a Platform to Explore Polyglutamine Toxicity and Aggregation -- Immunobased Detection Assays to Quantify Distinct Mutant Huntingtin Conformations in Biological Samples -- Modeling and Analysis of Repeat RNA Toxicity in Drosophila -- Analyzing Modifiers of Protein Aggregation in C. elegans by Native Agarose Gel Electrophoresis -- Kinetic Analysis of Aggregation Data -- A Bioinformatics Method for Identifying Q/N-rich Prion-like Domains in Proteins -- Detecting Soluble PolyQ Oligomers and Investigating their Impact on Living Cells using Split-GFP -- Cell Biological Approaches To Investigate Polyglutamine-Expanded AR Metabolism.
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| 650 |
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0 |
|a Human genetics.
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| 650 |
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0 |
|a Medical genetics.
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| 650 |
1 |
4 |
|a Human Genetics.
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| 650 |
2 |
4 |
|a Gene Function.
|
| 700 |
1 |
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|a Hatters, Danny M.
|e editor.
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| 700 |
1 |
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|a Hannan, Anthony J.
|e editor.
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| 710 |
2 |
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|a SpringerLink (Online service)
|
| 773 |
0 |
|
|t Springer eBooks
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| 900 |
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|a Libro descargado a ALEPH en bloque (proveniente de proveedor)
|