Tandem Repeats in Genes, Proteins, and Disease : Methods and Protocols /

Detalles Bibliográficos
Autor Corporativo: SpringerLink (Online service)
Otros Autores: Hatters, Danny M. (Editor ), Hannan, Anthony J. (Editor )
Formato: eBook
Lenguaje:English
Publicado: Totowa, NJ : Humana Press : Imprint: Humana, 2013.
Edición:1st ed. 2013.
Colección:Methods in Molecular Biology, 1017
Materias:
Tabla de Contenidos:
  • Longitudinal Imaging and Analysis of Neurons Expressing Polyglutamine-Expanded Proteins
  • Atomic Force Microscopy Assays for Evaluating Polyglutamine Aggregation in Solution and on Surfaces
  • Morphometric Analysis of Huntington’s Disease Neurodegeneration in Drosophila
  • Size Analysis of Polyglutamine Protein Aggregates using Fluorescence Detection in an Analytical Ultracentrifuge
  • A Method for the Incremental Expansion of Polyglutamine Repeats in Recombinant Proteins
  • Pulse Shape Analysis (PulSA) to Track Protein Translocalization in Cells by Flow Cytometry: Applications for Polyglutamine Aggregation
  • Characterizing Social Behavior in Genetically Targeted Mouse Models of Brain Disorders
  • PCR Amplification and Sequence Analysis of GC-rich Sequences: Aristaless-Related Homeobox Example
  • Challenges of “sticky” Co-Immunoprecipitation; Polyalanine Tract Protein-Protein Interactions
  • Molecular Pathology of Polyalanine Expansion Disorders-new Perspectives from Mouse Models
  • Yeast as a Platform to Explore Polyglutamine Toxicity and Aggregation
  • Immunobased Detection Assays to Quantify Distinct Mutant Huntingtin Conformations in Biological Samples
  • Modeling and Analysis of Repeat RNA Toxicity in Drosophila
  • Analyzing Modifiers of Protein Aggregation in C. elegans by Native Agarose Gel Electrophoresis
  • Kinetic Analysis of Aggregation Data
  • A Bioinformatics Method for Identifying Q/N-rich Prion-like Domains in Proteins
  • Detecting Soluble PolyQ Oligomers and Investigating their Impact on Living Cells using Split-GFP
  • Cell Biological Approaches To Investigate Polyglutamine-Expanded AR Metabolism.