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130605s2013 ne | s |||| 0|eng d |
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|a 9789400765702
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| 024 |
7 |
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|a 10.1007/978-94-007-6570-2
|2 doi
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| 040 |
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|a Sistema de Bibliotecas del Tecnológico de Costa Rica
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| 245 |
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|a Spotlight on Familial and Hereditary Gastric Cancer /
|c edited by Giovanni Corso, Franco Roviello.
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| 250 |
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|a 1st ed. 2013.
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| 260 |
# |
# |
|a Dordrecht :
|b Springer Netherlands :
|b Imprint: Springer,
|c 2013.
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| 300 |
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|a XVIII, 211 p. :
|b online resource.
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| 336 |
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|a text
|b txt
|2 rdacontent
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| 337 |
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|a computer
|b c
|2 rdamedia
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| 338 |
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|a online resource
|b cr
|2 rdacarrier
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|a Foreword -- Preface.-I General Issues -- Historical overview of familial gastric cancer -- Frequency of familial gastric cancer -- The family cancer database.- II Genetics and Epigenetics -- CDH1 gene, structure and function -- E-cadherin germline mutation -- Molecular mechanisms of hereditary diffuse gastric cancer initiation and progression -- Germline missense mutants in hereditary diffuse gastric cancer -- Alternative mechanisms to germline CDH1 mutations in hereditary diffuse gastric cancer -- Beyond CDH1 mutation-causes of hereditary gastric cancer -- Non-CDH1-associated familial gastric cancer and epigenetics factors.-III Pathology -- Hereditary diffuse gastric cancer and lobular breast carcinoma -- Pathology of hereditary diffuse gastric cancer.-IV Management -- Clinical criteria for familial gastric cancer definition -- Prophylactic total gastrectomy in CDH1 germline mutation carrier -- Gastric cancer in other inherited syndromes -- Clinical management of familial gastric cancer.- Appendix.- Index.
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| 650 |
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|a Cancer research.
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| 650 |
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|a Medicine.
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| 650 |
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|a Gastroenterology .
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| 650 |
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|a Human genetics.
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| 650 |
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4 |
|a Cancer Research.
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| 650 |
2 |
4 |
|a Biomedicine, general.
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| 650 |
2 |
4 |
|a Gastroenterology.
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| 650 |
2 |
4 |
|a Human Genetics.
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| 700 |
1 |
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|a Corso, Giovanni.
|e editor.
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| 700 |
1 |
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|a Roviello, Franco.
|e editor.
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| 710 |
2 |
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|a SpringerLink (Online service)
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| 773 |
0 |
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|t Springer eBooks
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