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150219s2015 xxu| s |||| 0|eng d |
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|a 9781493923304
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| 024 |
7 |
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|a 10.1007/978-1-4939-2330-4
|2 doi
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| 040 |
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|a Sistema de Bibliotecas del Tecnológico de Costa Rica
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| 245 |
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|a Rhodopsin :
|b Methods and Protocols /
|c edited by Beata Jastrzebska.
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| 250 |
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|a 1st ed. 2015.
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| 260 |
# |
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|a New York, NY :
|b Springer New York :
|b Imprint: Humana,
|c 2015.
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| 300 |
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|a XIV, 414 p. 94 illus., 71 illus. in color. :
|b online resource.
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| 336 |
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|a text
|b txt
|2 rdacontent
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| 337 |
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|a computer
|b c
|2 rdamedia
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| 338 |
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|a online resource
|b cr
|2 rdacarrier
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| 490 |
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|a Methods in Molecular Biology,
|v 1271
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| 505 |
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|a The G Protein-Coupled Receptor Rhodopsin: A Historical Perspective -- Rhodopsin Purification from Dark Adapted Bovine Retina -- Mammalian Expression, Purification, and Crystallization of Rhodopsin Variants -- Imaging of Rhodopsin Crystals with Two-Photon Microscopy -- Functional Stability of Rhodopsin in a Bicelle System: Evaluating G-Protein Activation by Rhodopsin in Bicelles -- The Rhodopsin-Arrestin-1 Interaction in Bicelles -- Detection of Structural Waters and Their Role in Structural Dynamics of Rhodopsin Activation -- Probing Conformational Changes in Rhodopsin Using Hydrogen-Deuterium Exchange Coupled to Mass Spectrometry -- Analysis of Conformational Changes in Rhodopsin by Histidine Hydrogen-Deuterium Exchange -- Investigation of Rhodopsin Dynamics in its Signaling State by Solid-State Deuterium NMR Spectroscopy -- Sequential Structural Changes in Rhodopsin Occurring upon Photoactivation -- Dynamic Single-Molecule Force Spectroscopy of Rhodopsin in Native Membranes -- High-Resolution Atomic Force Microscopy Imaging of Rhodopsin in Rod Outer Segment Disk Membranes -- Detection of Rhodopsin Dimerization in situ by PIE-FCCS, a Time-Resolved Fluorescence Spectroscopy -- Oligomeric State of Rhodopsin within Rhodopsin-Transducin Complex Probed with Succinylated Concanavalin A -- Quantification of Arrestin-Rhodopsin Binding Stoichiometry -- Rhodopsin Transient Complexes Investigated by Systems Biology Approaches -- Three Dimensional Architecture of Murine Rod Cilium Revealed by Cryo-EM -- Monitoring of Rhodopsin Trafficking and Mistrafficking in Live Photoreceptors -- Measurements of Rhodopsin Diffusion within Signaling Membrane Microcompartments in Live Photoreceptors -- Kinetics of Rhodopsin’s Chromophore Monitored in a Single Photoreceptor -- Supplementation with Vitamin A Derivatives to Rescue Vision in Animal Models of Degenerative Retinal Diseases -- Sustained Delivery of Retinoids to Prevent Photoreceptor Death -- High-Throughput Screening Assays to Identify Small-Molecules Preventing Photoreceptor Degeneration Caused by the Rhodopsin P23H Mutation -- Gene Therapy to Rescue Retinal Degeneration Caused by Mutations in Rhodopsin.
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| 650 |
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|a Cell biology.
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| 650 |
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|a Proteomics.
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| 650 |
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|a Cell membranes .
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| 650 |
1 |
4 |
|a Cell Biology.
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| 650 |
2 |
4 |
|a Proteomics.
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| 650 |
2 |
4 |
|a Membrane Biology.
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| 700 |
1 |
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|a Jastrzebska, Beata.
|e editor.
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| 710 |
2 |
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|a SpringerLink (Online service)
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| 773 |
0 |
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|t Springer eBooks
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