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170321s2017 xxu| s |||| 0|eng d |
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|a 9781493968923
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| 024 |
7 |
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|a 10.1007/978-1-4939-6892-3
|2 doi
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| 040 |
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|a Sistema de Bibliotecas del Tecnológico de Costa Rica
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| 245 |
1 |
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|a Telomeres and Telomerase :
|b Methods and Protocols /
|c edited by Zhou Songyang.
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| 250 |
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|a 3rd ed. 2017.
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| 260 |
# |
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|a New York, NY :
|b Springer New York :
|b Imprint: Humana,
|c 2017.
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| 300 |
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|a XI, 218 p. 37 illus., 18 illus. in color. :
|b online resource.
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| 336 |
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|a text
|b txt
|2 rdacontent
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| 337 |
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|a computer
|b c
|2 rdamedia
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| 338 |
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|a online resource
|b cr
|2 rdacarrier
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| 490 |
1 |
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|a Methods in Molecular Biology,
|v 1587
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| 505 |
0 |
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|a Introduction to Telomeres and Telomerase -- Analysis of Average Telomere Length in Human Telomeric Protein Knockout Cells Generated by CRISPR/Cas9 -- Telomere Length Analysis by Quantitative Fluorescent In Situ Hybridization (Q-FISH) -- Telomere Strand-Specific Length Analysis by Fluorescent In Situ Hybridization (Q-CO-FISH) -- Telomere G-Rich Overhang Length Measurement: DSN Method -- Telomere G-Overhang Length Measurement Method 2: G-Tail Telomere HPA -- Telomere Terminal G/C Strand Synthesis: Measuring Telomerase Action and C-Rich Fill-In -- Analysis of Yeast Telomerase by Primer Extension Assays -- Assessing Telomerase Activities in Mammalian Cells Using the Quantitative PCR-Based Telomeric Repeat Amplification Protocol (qTRAP) -- Telomeres and NextGen CO-FISH: Directional Genomic Hybridization (Telo-dGH™) -- Visualization of Human Telomerase Localization by Fluorescence Microscopy Techniques -- Cytogenetic Analysis of Telomere Dysfunction -- Probing the Telomere Damage Response -- Induction of Site-Specific Oxidative Damage at Telomeres by Killerred-Fused Shelretin Proteins -- Using Protein-Fragment Complementation Assays (PCA) and Peptide Arrays to Study Telomeric Protein–Protein Interactions -- In Vitro Preparation and Crystallization of Vertebrate Telomerase Subunits -- Human Telomeric G-Quadruplex Structures and G-Quadruplex-Interactive Compounds -- Analysis of Telomere-Homologous DNA with Different Conformations Using 2D Agarose Electrophoresis and In-Gel Hybridization -- Analysis of Telomere Proteins by Chromatin Immunoprecipitation (ChIP). .
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| 650 |
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|a Biochemistry.
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| 650 |
1 |
4 |
|a Biochemistry, general.
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| 700 |
1 |
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|a Songyang, Zhou.
|e editor.
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| 710 |
2 |
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|a SpringerLink (Online service)
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| 773 |
0 |
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|t Springer eBooks
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