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02122nam a22003015i 4500 |
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cr nn 008mamaa |
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120106s2012 xxu| s |||| 0|eng d |
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|a 9781617795206
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| 024 |
7 |
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|a 10.1007/978-1-61779-520-6
|2 doi
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| 040 |
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|a Sistema de Bibliotecas del Tecnológico de Costa Rica
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| 245 |
1 |
0 |
|a Structure-Based Drug Discovery /
|c edited by Leslie W. Tari.
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| 250 |
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|a 1st ed. 2012.
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| 260 |
# |
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|a Totowa, NJ :
|b Humana Press :
|b Imprint: Humana,
|c 2012.
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| 300 |
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|a IX, 385 p. 130 illus., 5 illus. in color. :
|b online resource.
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| 336 |
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|a text
|b txt
|2 rdacontent
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| 337 |
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|a computer
|b c
|2 rdamedia
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| 338 |
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|a online resource
|b cr
|2 rdacarrier
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| 490 |
1 |
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|a Methods in Molecular Biology,
|v 841
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| 505 |
0 |
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|a The Utility of Structural Biology in Drug Discovery -- Genetic Construct Design and Recombinant Protein Expression for Structural Biology -- Purification of Proteins for Crystallographic Applications -- Protein Crystallization for Structure-Based Drug Design -- X-Ray Sources and High-Throughput Data Collection Methods -- The Use of Molecular Graphics in Structure-Based Drug Design -- Crystallographic Fragment Screening -- The Role of Enzymology in a Structure-Based Drug Discovery Program: Bacterial DNA Gyrase -- Leveraging Structural Information for the Discovery of New Drugs: Computational Methods -- Chemical Informatics - Using Molecular Shape Descriptors in Structure-Based Drug Design -- Accounting for Solvent in Structure-Based Drug Design -- Structure-Based Drug Design on Membrane Protein Targets: Human Integral Membrane Protein 5-Lipoxygenase-Activating Protein -- Application of SBDD to the Discovery of New Antibacterial Drugs -- Leveraging SBDD in Protein Therapeutic Development: Antibody Engineering -- A Medicinal Chemistry Perspective on Structure-Based Drug Design and Development.
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| 650 |
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|a Pharmacology.
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| 650 |
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|a Medicinal chemistry.
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| 650 |
1 |
4 |
|a Pharmacology/Toxicology.
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| 650 |
2 |
4 |
|a Medicinal Chemistry.
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| 700 |
1 |
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|a Tari, Leslie W.
|e editor.
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| 710 |
2 |
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|a SpringerLink (Online service)
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| 773 |
0 |
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|t Springer eBooks
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