Transformative Concepts for Drug Design: Target Wrapping /
| Autor principal: | |
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| Autor Corporativo: | |
| Formato: | eBook |
| Lenguaje: | English |
| Publicado: |
Berlin, Heidelberg :
Springer Berlin Heidelberg : Imprint: Springer,
2010.
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| Edición: | 1st ed. 2010. |
| Materias: |
Tabla de Contenidos:
- Protein Cooperativity and Wrapping: Two Themes in the Transformative Platform of Molecular Targeted Therapy
- Wrapping Defects and the Architecture of Soluble Proteins
- Folding Cooperativity and the Wrapping of Intermediate States of Soluble Natural Proteins
- Wrapping Deficiencies and De-wetting Patterns in Soluble Proteins: A Blueprint for Drug Design
- Under-Wrapped Proteins in the Order–Disorder Twilight: Unraveling the Molecular Etiology of Aberrant Aggregation
- Evolution of Protein Wrapping and Implications for the Drug Designer
- Wrapping as a Selectivity Filter for Molecular Targeted Therapy: Preliminary Evidence
- Re-engineering an Anticancer Drug to Make It Safer: Modifying Imatinib to Curb Its Side Effects
- Wrapping Patterns as Universal Markers for Specificity in the Therapeutic Interference with Signaling Pathways
- Fulfilling a Therapeutic Imperative in Cancer Treatment: Control of Multi-target Drug Impact
- Inducing Folding By Crating the Target
- Wrapper Drugs as Therapeutic Editors of Side Effects
- Wrapper Drugs for Personalized Medicine
- Last Frontier and Back to the Drawing Board: Protein–Water Interfacial Tension in Drug Design.